Browsing Centro de Biología Integrativa (CBI) by Subject "CIENCIAS BIOLÓGICAS"

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Altered potassium channel distribution and composition in myelinated axons suppresses hyperexcitability following injury

Richards, Natalie [Wolfson Centre for Age-Related Diseases, Kings College London, London,United Kingdom]; Schmid, Annina B. [University of Oxford, Oxford. Nuffield Department of Clinical Neurosciences]; Barroso, Alejandro [Reino Unido. Wolfson Centre for Age-Related Diseases]; Zhu, Lan [Reino Unido. Wolfson Centre for Age-Related Diseases]; Ivulic, Dinka [Pontificia Universidad Católica de Chile]; Zhu, Ning [Reino Unido. University of Oxford. Nuffield Department of Clinical Neurosciences]; Anwandter, Philipp [Pontificia Universidad Católica de Chile]; Manzoor, Bhat A. [Estados Unidos. UT Health Science Center at San Antonio] (CIENCIAS, 2016)

Neuropathic pain following peripheral nerve injury is associated with hyperexcitability in damaged myelinated sensory axons, which begins to normalise over time. We investigated the composition and distribution of ...
Origin of axonal proteins: Is the axon-schwann cell unit a functional syncytium?

Alvarez, Jaime [Chile. Universidad Mayor. Facultad de Ciencias]; Court, Felipe A. [Chile. Universidad Mayor. Facultad de Ciencias] (CIENCIAS, 2016)

The structural homeostasis is challenging for neurons, whose axons extend up to meters in large animals, and the axoplasmic mass reaches over a thousand times that of the cell body. Thus, the protein demand may overcome ...