Browsing Centro de Biología Integrativa (CBI) by Subject "Cell Biology; Geriatrics & Gerontology"

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Down syndrome and Alzheimer's disease: common molecular traits beyond the amyloid precursor protein

Nassif, Melissa [Univ Mayor, Fac Sci, Ctr Integrat Biol, Lab Neuroprotect & Autophagy, Santiago, Chile]; Gómez, Wileidy [Univ Mayor, Fac Sci, Ctr Integrat Biol, Lab Neuroprotect & Autophagy, Santiago, Chile]; Morales, Rodrigo; Maracaja-Coutinho, Vinicius; Parra, Valentina (IMPACT JOURNALS LLC, 2020)

Alzheimer's disease (AD) is the most prevalent type of dementia. Down syndrome (DS) is the leading genetic risk factor for Early-Onset AD, prematurely presenting the classic pathological features of the brain with AD. ...