Browsing Centro de Biología Integrativa (CBI) by Subject "FACTOR-II/MANNOSE-6-PHOSPHATE RECEPTOR"

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Insulin-like growth factor 2 (IGF2) protects against Huntington's disease through the extracellular disposal of protein aggregates

García-Huerta, Paula; Troncoso-Escudero, Paulina Oñate, Maritza [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Wu, Di; Thiruvalluvan, Arun; Cisternas-Olmedo, Marisol [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Henríquez, Daniel R.; Plate, Lars; Chana-Cuevas, Pedro; Saquel, Cristian [Ctr Integrat Biol, Fac Sci, Universidad Mayor, Chile]; Thielen, Peter; Longo, Kenneth A.; Geddes, Brad J.Lederkremer, Gerardo Z.; Sharma, Neeraj; Shenkman, Marina; Naphade, Swati; Sardi, S. Pablo; Spichiger, Carlos; Richter, Hans G.; Court, Felipe A.; Tshilenge, Kizito Tshitoko; Ellerby, Lisa M.; Wiseman, R. Luke; Gonzalez-Billault, Christian; Bergink, Steven; Vidal, Rene L.; Hetz, Claudio (SPRINGER, 2020-11)

Impaired neuronal proteostasis is a salient feature of many neurodegenerative diseases, highlighting alterations in the function of the endoplasmic reticulum (ER). We previously reported that targeting the transcription ...