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Conversatorio: Hacia el envejecimiento saludable en Chile
(Chile. Universidad Mayor, 2021-01-21)
El conversatorio en línea "Hacia el envejecimiento saludable en Chile" organizado por la Facultad de Ciencias de la Universidad Mayor y Abbott, compañía multinacional de alta tecnología en salud. En la convocatoria, ...
La Ruta del Pensamiento: una mirada actual al cáncer en Chile
(Chile. Universidad Mayor, 2021-08-20)
El Doctor en Ciencias Biológicas e investigador del Centro de Biología Integrativa de la Universidad Mayor, Erick Riquelme, aborda el proceso de los tumores, los principales tratamientos, los últimos hallazgos para futuros ...
La Ruta del Pensamiento: ¿Qué sabemos de las enfermedades que afectan al cerebro?
(Chile. Universidad Mayor, 2021-07-28)
René Vidal, Doctor en Ciencias y académico del Centro de Biología Integrativa U. Mayor, realizó el webinar “¿Qué sabemos de las enfermedades que afectan al cerebro?”, donde profundizó en su funcionamiento y qué ocurre ...
Association of Vitamin D Receptor Polymorphisms with Amyloid-β Transporters Expression and Risk of Mild Cognitive Impairment in a Chilean Cohort
(IOS PRESS, 2021-07-15)
Background: Amyloid-beta peptide (A beta) deposition in Alzheimer's disease (AD) is due to an imbalance in its production/clearance rate. Ap is transported across the blood-brain barrier by LRP1 and P-gp as efflux transporters ...
Levels of low-molecular-weight hyaluronan in periodontitis-treated patients and its immunostimulatory effects on CD4+ T lymphocytes
(SPRINGER HEIDELBERG, 2021-02-26)
Objectives During periodontitis, chronic inflammation triggers soft tissue breakdown, and hyaluronan is degraded into fragments of low molecular weight (LMW-HA). This investigation aimed to elucidate whether LMW-HA fragments ...
Antisense noncoding mitochondrial RNA-2 gives rise to miR-4485-3p by Dicer processing in vitro
(SOC BIOLGIA CHILE, 2021-10-19)
Background The antisense noncoding mitochondrial RNAs (ASncmtRNAs) derive from the mitochondrial 16S gene. Knockdown of these transcripts with chemically-modified antisense oligonucleotides induces proliferative arrest, ...
IRE1α RIDD activity induced under ER stress drives neuronal death by the degradation of 14-3-3 θ mRNA in cortical neurons during glucose deprivation
(SPRINGER NATURE, 2021-06-03)
Altered protein homeostasis is associated with neurodegenerative diseases and acute brain injury induced under energy depletion conditions such as ischemia. The accumulation of damaged or unfolded proteins triggers the ...
In Vivo Antitumor Effect against Murine Cells of CT26 Colon Cancer and EL4 Lymphoma by Autologous Whole Tumor Dead Cells
(HINDAWI LTD, 2021-03-14)
Active immunotherapy against cancer is based on immune system stimulation, triggering efficient and long-lasting antigen-specific immune responses. Immunization strategies using whole dead cells from tumor tissue, containing ...
Pangenome analysis reveals genetic isolation in Campylobacter hyointestinalis subspecies adapted to different mammalian hosts
(NATURE PORTFOLIO, 2021-02-09)
Campylobacter hyointestinalis is an emerging pathogen currently divided in two subspecies: C. hyointestinalis subsp. lawsonii which is predominantly recovered from pigs, and C. hyointestinalis subsp. hyointestinalis which ...
A global metagenomic map of urban microbiomes and antimicrobial resistance
(CELL PRESS, 2021-06-24)
We present a global atlas of 4,728 metagenomic samples from mass-transit systems in 60 cities over 3 years, representing the first systematic, worldwide catalog of the urban microbial ecosystem. This atlas provides an ...