Listar Papers publicados por CBI por autor "Ahumada-Castro, Ulises [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]"
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Inhibition of InsP3R with Xestospongin B Reduces Mitochondrial Respiration and Induces Selective Cell Death in T Cell Acute Lymphoblastic Leukemia Cells
Cruz, Pablo [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Ahumada-Castro, Ulises [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Bustos, Galdo [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Molgo, Jordi; Sauma, Daniela; Lovy, Alenka [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Cárdenas, Cesar [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile] (MDPI, 2021-01)T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy whose chemoresistance and relapse persist as a problem despite significant advances in its chemotherapeutic treatments. Mitochondrial ... -
Keeping zombies alive: The ER-mitochondria Ca2+ transfer in cellular senescence
Ahumada-Castro, Ulises [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Puebla-Huerta, Andrea [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Cuevas-Espinoza, Victor [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Lovy, Alenka [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Cesar Cardenas, J. [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile] (ELSEVIER, 2021-08-31)Cellular senescence generates a permanent cell cycle arrest, characterized by apoptosis resistance and a pro-inflammatory senescence-associated secretory phenotype (SASP). Physiologically, senescent cells promote tissue ...