Listar Papers publicados por CBI por autor "Lovy, Alenka [Univ Mayor, Ctr Integrat Biol, Fac Sci, Chile]"
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Ca2+ transfer to mitochondria: a spark of life in unexpected conditions
Silva-Pavez, E. [Univ Mayor, Ctr Integrat Biol, Fac Sci, Chile]; Ahumada-Castro, U. [Univ Mayor, Ctr Integrat Biol, Fac Sci, Chile]; Lovy, Alenka [Univ Mayor, Ctr Integrat Biol, Fac Sci, Chile]; Cárdenas, Julio César [Univ Mayor, Ctr Integrat Biol, Fac Sci, Chile] (Chile. Universidad Mayor, 2020)The inositol 1,4,5-triphosphate receptor (InsP3R)-mediated calcium (Ca2+) transfer to mitochondria is important to maintain mitochondrial respiration and bioenergetics in normal and cancer cells, even though cancer cells ... -
Cancer cells with defective oxidative phosphorylation require endoplasmic reticulum-to-mitochondria Ca2+ transfer for survival
Cárdenas, César [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Lovy, Alenka [Univ Mayor, Ctr Integrat Biol, Fac Sci, Chile]; Silva-Pavez, Eduardo [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Urra, Felix; Mizzoni, Craig; Ahumada-Castro, Ulises; Bustos, Galdo [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Jana, Fabián; Cruz, Pablo [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Farías, Paula [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Mendoza, Elizabeth [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Huerta, Hernán [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Murgas, Paola [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Hunter, Martin; Róos, Melany [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Cerda, Oscar; Georgakoudi, Irene; Zakarian, Armen; Molgo, Jordi; Foskett, J. Kevin (American Association for the Advancement of Science, 2020-07)Spontaneous Ca2+ signaling from the InsP(3)R intracellular Ca2+ release channel to mitochondria is essential for optimal oxidative phosphorylation (OXPHOS) and ATP production. In cells with defective OXPHOS, reductive ... -
Concerted Action of AMPK and Sirtuin-1 Induces Mitochondrial Fragmentation Upon Inhibition of Ca(2+)Transfer to Mitochondria
Lovy, Alenka [Univ Mayor, Ctr Integrat Biol, Fac Sci, Chile]; Ahumada-Castro, Ulises [Univ Mayor, Ctr Integrat Biol, Fac Sci, Chile]; Bustos, Galdo [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Farias, Paula [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Gonzalez-Billault, Christian [Univ Mayor, Fac Sci, Gerosci Ctr Brain Hlth & Metab, Chile]; Molgo, Jordi; Cardenas, Cesar [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile] (Frontiers Media S.A., 2020-05)Mitochondria are highly dynamic organelles constantly undergoing fusion and fission. Ca(2+)regulates many aspects of mitochondrial physiology by modulating the activity of several mitochondrial proteins. We previously ...