• ConnecTF: A platform to integrate transcription factor-gene interactions and validate regulatory networks 

      Brooks, Matthew D.; Juang, Che-Lun; Katari, Manpreet Singh; Pasquino, Angelo; Shih, Hung-Jui; Huang, Ji; Shanks, Carly; Cirrone, Jacopo; Coruzzi, Gloria M.; Alvarez, Jose M. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile] (OXFORD UNIV PRESS INC, 2021-04-28)
      Deciphering gene regulatory networks (GRNs) is both a promise and challenge of systems biology. The promise lies in identifying key transcription factors (TFs) that enable an organism to react to changes in its environment. ...
    • Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade 

      Alvarez, Jose M. [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Schinke, Anna-Lena; Brooks, Matthew D.; Pasquino, Angelo; Leonelli, Lauriebeth; Varala, Kranthi; Safi, Alaeddine; Krouk, Gabriel; Krapp, Anne; Coruzzi, Gloria M. (Nature Publishing Group, 2020-03-02)
      Dynamic reprogramming of gene regulatory networks (GRNs) enables organisms to rapidly respond to environmental perturbation. However, the underlying transient interactions between transcription factors (TFs) and genome-wide ...


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