• A HaloTag-TEV genetic cassette for mechanical phenotyping of proteins from tissues 

      Rivas-Pardo, Jaime Andrés [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Li, Yong; Martonfalvi, Zsolt; Tapia-Rojo, Rafael; Unger, Andreas; Fernández-Trasancos, Angel; Herrero-Galán, Elías; Velázquez-Carreras, Diana; Fernández, Julio M.; Linke, Wolfgang A.; Alegre-Cebollada, Jorge (Nature Publishing Group, 2020-04-28)
      Single-molecule methods using recombinant proteins have generated transformative hypotheses on how mechanical forces are generated and sensed in biological tissues. However, testing these mechanical hypotheses on proteins ...
    • Interfering with the Folding of Group A Streptococcal pili Proteins 

      Contreras, Fernanda [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Rivas-Pardo, Jaime Andrés [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile] (Chile. Universidad Mayor, 2020-05-20)
      Gram-positive bacteria use their adhesive pili to attach to host cells during early stages of a bacterial infection. These extracellular hair-like appendages experience mechanical stresses of hundreds of picoNewtons; ...
    • Single-Nucleotide Polymorphisms (SNP) Mining and Their Effect on the Tridimensional Protein Structure Prediction in a Set of Immunity-Related Expressed Sequence Tags (EST) in Atlantic Salmon (Salmo salar) 

      Vallejos-Vidal, Eva; Reyes-Cerpa, Sebastián [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Rivas-Pardo, Jaime Andrés [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Maisey, Kevin; Yañez, José M.; Valenzuela, Héctor; Cea, Pablo A.; Castro-Fernández, Víctor; Tort, Lluis; Sandino, Ana M.; Imarai, Mónica; Reyes-López, Felipe E. (Frontiers Media S.A., 2020-02-27)
      Single-nucleotide polymorphisms (SNPs) are single genetic code variations considered one of the most common forms of nucleotide modifications. Such SNPs can be located in genes associated to immune response and, therefore, ...


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