Recent Submissions

  • Comparative genomics sheds light on transcription factor-mediated regulation in the extreme acidophilic Acidithiobacillia representatives 

    Sepúlveda-Rebolledo, Pedro [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; González-Rosales, Carolina; Dopson, Mark; Pérez-Rueda, Ernesto; Holmes, David S.; Valdés, Jorge H. (Elsevier Masson s.r.l., 2024-01)
    Extreme acidophiles thrive in acidic environments, confront a multitude of challenges, and demonstrate remarkable adaptability in their metabolism to cope with the ever-changing environmental fluctuations, which encompass ...
  • Anaerobic RSH-dependent tellurite reduction contributes to Escherichia coli tolerance against tellurite 

    Muñoz-Diaz, P.; Jiménez, K.; Luraschi, R.; Cornejo, F.; Figueroa, M.; Vera, C.; Rivas-Pardo, A. [Univ Mayor, Ctr Genom & Bioinformat, Lab Genom Microbiana, Chile]; Sandoval, J. M.; Vásquez, C.; Arenas, F. (SOC BIOLGIA CHILE, 2022-03)
    Background Tellurium is a rare metalloid that exerts high toxicity on cells, especially on bacteria, partly due to reactive oxygen species (ROS) generation. Moreover, it has also been observed that tellurite can target ...
  • Development of a Multiplex PCR Assay for Genotyping the Fish Pathogen Piscirickettsia salmonis Through Comparative Genomics 

    Isla, Adolfo; Martínez-Hernández, J. Eduardo [Univ Mayor, Ctr Genom & Bioinformat, Fac Ciencias, Laboratorio Biol Redes, Chile]; Levipan, Héctor A.; Haussmann, Denise; Figueroa, Jaime; Rauch, María Cecilia; Maracaja-Coutinho, Vinicius; Yáñez, Alejandro (FRONTIERS MEDIA SA, 2021-07-11)
    Piscirickettsia salmonis is a bacterial pathogen that severely impact the aquaculture in several countries as Canada, Scotland, Ireland, Norway, and Chile. It provokes Piscirickettsiosis outbreaks in the marine phase of ...
  • TGA class II transcription factors are essential to restrict oxidative stress in response to UV-B stress in Arabidopsis 

    Herrera-Vásquez, Ariel; Fonseca, Alejandro; Ugalde, José Manuel; Lamig, Liliana; Seguel, Aldo; Moyano, Tomas C.; Gutiérrez, Rodrigo A.; Salinas, Paula; Vidal, Elena A. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile]; Holuigue, Loreto (OXFORD UNIV PRESS, 2021-02-27)
    Plants possess a robust metabolic network for sensing and controlling reactive oxygen species (ROS) levels upon stress conditions. Evidence shown here supports a role for TGA class II transcription factors as critical ...
  • Metabolite Fruit Profile Is Altered in Response to Source-Sink Imbalance and Can Be Used as an Early Predictor of Fruit Quality in Nectarine 

    Covarrubias, María Paz; Lillo-Carmona, Victoria; Melet, Lorena [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Huechuraba, Chile]; Benedetto, Gianfranco; Andrade, Diego; Maucourt, Mickael; Deborde, Catherine; Fuentealba, Claudia; Moing, Annick; Valenzuela, Maria Luisa; Pedreschi, Romina; Almeida, Andrea Miyasaka [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile] (FRONTIERS MEDIA SA, 2021-01-08)
    Peaches and nectarines [Prunus persica (L.) Batsch] are among the most exported fresh fruit from Chile to the Northern Hemisphere. Fruit acceptance by final consumers is defined by quality parameters such as the size, ...
  • Filtering of Data-Driven Gene Regulatory Networks Using Drosophila melanogaster as a Case Study 

    Cuesta-Astroz, Yesid; Gischkow Rucatti, Guilherme [Univ Mayor, Fac Ciencias, Ctr Biol Integrat, Chile]; Murgas, Leandro [Univ Mayor, Lab Biol Redes, Ctr Genom & Bioinformat, Fac Ciencias, Chile]; SanMartin, Carol D.; Sanhueza, Mario [Univ Mayor, Fac Ciencias, Ctr Biol Integrat, Chile]; Martin, Alberto J. M. [Univ Mayor, Lab Biol Redes, Ctr Genom & Bioinformat, Fac Ciencias, Chile] (FRONTIERS MEDIA SA, 2021-07-28)
    Gene Regulatory Networks (GRNs) allow the study of regulation of gene expression of whole genomes. Among the most relevant advantages of using networks to depict this key process, there is the visual representation of large ...
  • SinEx DB 2.0 update 2020: database for eukaryotic single-exon coding sequences 

    Jorquera, R; Clausen, PTLC; Petersen, B.; González, C. [Univ Mayor, Ctr Genom & Bioinformat, Chile]; Holmes, DS [Univ Mayor, Ctr Genom & Bioinformat, Chile] (Oxford University Press, 2021-01-28)
    Single-exon coding sequences (CDSs), also known as 'single-exon genes' (SEGs), are defined as nuclear, protein-coding genes that lack introns in their CDSs. They have been studied not only to determine their origin and ...
  • Levels of low-molecular-weight hyaluronan in periodontitis-treated patients and its immunostimulatory effects on CD4+ T lymphocytes 

    Castillo, Francisca; Monasterio, Gustavo; Ibarra, Juan; Guevara, José; Cafferata, Emilio A.; Carvajal, Paola; Vernal, Rolando; Vicencio, Emiliano [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Cortez, Cristian [Univ Mayor, Fac Sci, Ctr Genom & Bioinformat, Chile] (SPRINGER HEIDELBERG, 2021-02-26)
    Objectives During periodontitis, chronic inflammation triggers soft tissue breakdown, and hyaluronan is degraded into fragments of low molecular weight (LMW-HA). This investigation aimed to elucidate whether LMW-HA fragments ...
  • ConnecTF: A platform to integrate transcription factor-gene interactions and validate regulatory networks 

    Brooks, Matthew D.; Juang, Che-Lun; Katari, Manpreet Singh; Pasquino, Angelo; Shih, Hung-Jui; Huang, Ji; Shanks, Carly; Cirrone, Jacopo; Coruzzi, Gloria M.; Alvarez, Jose M. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile] (OXFORD UNIV PRESS INC, 2021-04-28)
    Deciphering gene regulatory networks (GRNs) is both a promise and challenge of systems biology. The promise lies in identifying key transcription factors (TFs) that enable an organism to react to changes in its environment. ...
  • A decade later, reviewing floating marine debris in Northern Chilean Patagonia 

    Ahrendt, C.; DeCoite, M.; Pulgar, J.; Pozo, K.; Hinojosa, I. A.; Galban-Malagon, C. [Univ Mayor, GEMA Ctr Genom Ecol & Environm, Chile] (PERGAMON-ELSEVIER SCIENCE LTD, 2021-07-07)
    Floating marine debris (FMD) were abundantly reported in the Northern Chilean Patagonia in 2009 where seabased activities (mussel and salmon aquaculture) are responsible for most of them. Identifying the sources of FMD is ...
  • Multiplex TaqMan Real-Time PCR Assay for Sensitive Detection of Two Weevil Species (Coleoptera: Curculionidae) 

    Aguirre, Carlos; Olivares, Natalia; Hinrichsen, Patricio; Sanchez, Evelyn [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile] (OXFORD UNIV PRESS INC, 2021-06-04)
    Rapid and cost-efficient identification of Naupactus species is becoming a key process for the exportation of citrus fruit from Chile and other countries, considering the quarantine regulations for some species of the ...
  • Non-Specific Antibodies Induce Lysosomal Activation in Atlantic Salmon Macrophages Infected by Piscirickettsia salmonis 

    Pérez-Stuardo, Diego [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile]; Espinoza, Allison [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile]; Tapia, Sebastián [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile]; Morales-Reyes, Jonathan; Barrientos, Claudio; Vallejos-Vidal, Eva; Sandino, Ana M.; Spencer, Eugenio; Toro-Ascuy, Daniela; Rivas-Pardo, J. Andrés [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile]; Reyes-López, Felipe E.; Reyes-Cerpa, Sebastián [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile] (Frontiers Media S.A., 2020-11)
    Piscirickettsia salmonis, an aggressive intracellular pathogen, is the etiological agent of salmonid rickettsial septicemia (SRS). This is a chronic multisystemic disease that generates high mortalities and large losses ...
  • In vitropropagation ofLeptocarpha rivularis, a native medicinal plant 

    Dorta, Fernando; Polanco, Víctor [Univ Mayor, Ctr Genom & Bioinformat, Fac Ciencias, Chile]; Ramírez, Ingrid; Seeger, Michael; Madrid, Alejandro; Montenegro, Iván (Springer New York, 2020-12)
    Leptocarpha rivularis, commonly known as "palo negro", is a species of the Astereaceae family, endemic in the forests of Southern Chile. The extracts of this plant have medicinal properties attributable to its secondary ...
  • Implications of Selective Autophagy Dysfunction for ALS Pathology 

    Vicencio, Emiliano [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Beltrán, Sebastián [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Labrador, Luis [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Manque, Patricio [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Nassif, Melissa [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Woehlbier, Ute [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile] (MDPI Multidisciplinary Digital Publishing Institute, 2020-02)
    Amyotrophic lateral sclerosis (ALS) is a lethal neurodegenerative disorder that progressively affects motor neurons in the brain and spinal cord. Due to the biological complexity of the disease, its etiology remains unknown. ...
  • Nitrate in 2020: Thirty Years from Transport to Signaling Networks 

    Vidal, Elena A. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile]; Alvarez, Jose M. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile]; Araus, Viviana; Riveras, Eleodoro; Brooks, Matthew D.; Krouk, Gabriel; Ruffel, Sandrine; Lejay, Laurence; Crawford, Nigel M.; Coruzzi, Gloria M.; Gutierrez, Rodrigo A. (American Society of Plant Biologists, 2020-07)
    Nitrogen (N) is an essential macronutrient for plants and a major limiting factor for plant growth and crop production. Nitrate is the main source of N available to plants in agricultural soils and in many natural environments. ...
  • Outline of Fungi and fungus-like taxa 

    Wijayawardene, NN; Hyde, KD; Al-Ani, LKT; Tedersoo, L.; Haelewaters, D; Rajeshkumar, KC; Zhao, RL; Aptroot, A; Leontyev, DV; Saxena, RK; Tokarev, YS; Dai, DQ; Letcher, PM; Stephenson, SL; Ertz, D; Lumbsch, HT; Kukwa, M; Issi, IV; Phillips, AJL; Selbmann, L; Pfliegler, WP; Horvath, E; Bensch, K; Kirk, PM; Kolarikova, K; Raja, HA; Radek, R; Papp, V; Dima, B; Ma, J; Malosso, E; Takamatsu, S; Rambold, G; Gannibal, PB; Triebel, D; Gautam, AK; Avasthi, S; Suetrong, S; Timdal, E; Fryar, SC; Delgado, G; Reblova, M; Doilom, M; Dolatabadi, S; Pawlowska, JZ; Humber, RA; Kodsueb, R; Sanchez-Castro, I; Goto, BT; Silva, DKA; de Souza, FA; Oehl, FR; da Silva, GA; Silva, IR; Blaszkowski, J; Jobim, K; Maia, LC; Barbosa, FR; Fiuza, PO; Divakar, PK; Shenoy, BD; Castaneda-Ruiz, RF; Somrithipol, S; Lateef, AA; Karunarathna, SC; Tibpromma, S; Mortimer, PE; Wanasinghe, DN; Phookamsak, R; Xu, J; Wang, Y; Tian, F; Alvarado, P; Li, DW; Kusan, I; Matocec, N; Mesic, A; Tkalcec, Z; Maharachchikumbura, SSN; Papizadeh, M; Heredia, G; Wartchow, F; Bakhshi, M; Boehm, E; Youssef, N; Hustad, VP; Lawrey, JD; Santiago, ALCMA; Bezerra, JDP; Souza-Motta, CM; Firmino, AL; Tian, Q; Houbraken, J; Hongsanan, S; Tanaka, K; Dissanayake, AJ; Monteiro, JS; Grossart, HP; Suija, A; Weerakoon, G; Etayo, J; Tsurykau, A; Vazquez, V; Mungai, P ; Damm, U; Li, QR; Zhang, H; Boonmee, S; Lu, YZ; Becerra, AG; Kendrick, B; Brearley, FQ; Motiejunaite, J; Sharma, B; Khare, R; Gaikwad, S; Wijesundara, DSA; Tang, LZ; He, MQ; Flakus, A; Rodriguez-Flakus, P; Zhurbenko, MP; McKenzie, EHC; Stadler, M; Bhat, DJ; Liu, JK; Raza, M; Jeewon, R; Nassonova, ES; Prieto, M; Jayalal, RGU; Erdogdu, M; Yurkov, A; Schnittler, M; Shchepin, ON; Novozhilov, YK; Silva, AGS; Gentekaki, E; Liu, P; Cavender, JC; Kang, Y; Mohammad, S; Zhang, LF; Xu, RF; Li, YM; Dayarathne, MC; Ekanayaka, AH; Wen, TC; Deng, CY; Pereira, OL; Navathe, S; Hawksworth, DL; Fan, XL; Dissanayake, LS; Kuhnert, E; Thines, M; Madrid, H. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile] (Guizhou Key Laboratory of Agricultural Biotechnology, 2020)
    This article provides an outline of the classification of the kingdom Fungi (including fossil fungi. i.e. dispersed spores, mycelia, sporophores, mycorrhizas). We treat 19 phyla of fungi. These are Aphelidiomycota, Ascomycota, ...
  • Gene Regulatory Networks of Penicillium echinulatum 2HH and Penicillium oxalicum 114-2 Inferred by a Computational Biology Approach 

    Lenz, Alexandre Rafael; Galán-Vásquez, Edgardo; Balbinot, Eduardo; de Abreu, Fernanda Pessi; Souza de Oliveira, Nikael; da Rosa, Leticia Osorio; de Avila e Silva, Scheila; Camassola, Marli; Dillon, Aldo Jose Pinheiro; Pérez-Rueda, Ernesto [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile] (Frontiers Media S.A., 2020-10)
    Penicillium echinulatum 2HH and Penicillium oxalicum 114-2 are well-known cellulase fungal producers. However, few studies addressing global mechanisms for gene regulation of these two important organisms are available so ...
  • Dormant but Active: Chilling Accumulation Modulates the Epigenome and Transcriptome ofPrunus aviumDuring Bud Dormancy 

    Rothkegel, Karin; Sandoval, Paula; Soto, Esteban; Ulloa, Lissette; Riveros, Anibal; Lillo-Carmona, Victoria; Caceres-Molina, Javier; Almeida, Andrea Miyasaka [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile]; Meneses, Claudio (Frontiers Media S.A., 2020-07)
    Temperate deciduous fruit tree species like sweet cherry (Prunus avium) require long periods of low temperatures to trigger dormancy release and flowering. In addition to sequence-based genetic diversity, epigenetic variation ...
  • Deciphering the functional diversity of DNA-binding transcription factors in Bacteria and Archaea organisms 

    Flores-Bautista, Emanuel; Hernández-Guerrero, Rafael; Huerta-Saquero, Alejandro; Tenorio-Salgado, Silvia; Rivera-Gómez, Nancy; Romero, Alba; Antonio Ibarra, José; Pérez-Rueda, Ernesto [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile] (Public Library of Science, 2020-08)
    DNA-binding Transcription Factors (TFs) play a central role in regulation of gene expression in prokaryotic organisms, and similarities at the sequence level have been reported. These proteins are predicted with different ...
  • Bacterially produced metabolites protect C. elegans neurons from degeneration 

    Urrutia, Arles; García-Angulo, Víctor A. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile]; Fuentes, Andres [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile]; Caneo, Mauricio; Legue, Marcela [Univ Mayor, Fac Ciencias, Ctr Genom Integrat, Chile]; Urquiza, Sebastian [Univ Mayor, Fac Ciencias, Ctr Genom Integrat, Chile]; Delgado, Scarlett E. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile]; Ugalde, Juan [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile]; Burdisso, Paula; Calixto, Andrea [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile] (Public Library of Science, 2020-03)
    Caenorhabditis elegans and its cognate bacterial diet comprise a reliable, widespread model to study diet and microbiota effects on host physiology. Nonetheless, how diet influences the rate at which neurons die remains ...

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