| dc.contributor | TAYLOR & FRANCIS INC. | es |
| dc.contributor.author | Silva-Pavez, E. [Univ Mayor, Ctr Integrat Biol, Fac Sci, Chile] | |
| dc.contributor.author | Ahumada-Castro, U. [Univ Mayor, Ctr Integrat Biol, Fac Sci, Chile] | |
| dc.contributor.author | Lovy, Alenka [Univ Mayor, Ctr Integrat Biol, Fac Sci, Chile] | |
| dc.contributor.author | Cárdenas, Julio César [Univ Mayor, Ctr Integrat Biol, Fac Sci, Chile] | |
| dc.date.accessioned | 2021-10-25T21:50:07Z | |
| dc.date.available | 2021-10-25T21:50:07Z | |
| dc.date.issued | 2020 | |
| dc.identifier.citation | Silva-Pavez E, Ahumada-Castro U, Lovy A, Cárdenas JC. Ca2+ transfer to mitochondria: a spark of life in unexpected conditions. Mol Cell Oncol. 2020 Dec 15;8(1):1839341. doi: 10.1080/23723556.2020.1839341. PMID: 33553601; PMCID: PMC7849767. | es |
| dc.identifier.issn | 2372-3556 | |
| dc.identifier.other | WOS: 000599422500001 | |
| dc.identifier.other | Scopus: 2-s2.0-85097557257 | |
| dc.identifier.other | PMID: 33553601 | |
| dc.identifier.uri | http://repositorio.umayor.cl/xmlui/handle/sibum/8041 | |
| dc.identifier.uri | https://doi.org/10.1080/23723556.2020.1839341 | |
| dc.identifier.uri | https://pubmed.ncbi.nlm.nih.gov/33553601/ | |
| dc.identifier.uri | https://www.tandfonline.com/doi/abs/10.1080/23723556.2020.1839341?journalCode=kmco20 | |
| dc.description.abstract | The inositol 1,4,5-triphosphate receptor (InsP3R)-mediated calcium (Ca2+) transfer to mitochondria is important to maintain mitochondrial respiration and bioenergetics in normal and cancer cells, even though cancer cells have defective oxidative phosphorylation (OXPHOS). Here, we discuss how tumor mitochondria could become a feasible therapeutic target to treat tumors that depend on reductive carboxylation. | es |
| dc.description.sponsorship | This work was supported by NIH P30NS047243 (AL), ANID/FONDECYT no. 1160332 and 1200255 (CC) and ANID/FONDAP no. 15150012 (CC); fondecyt [1160332]; fondap [15150012]; fondecyt [1200255]. | es |
| dc.format.extent | 4 p., PDF | es |
| dc.language.iso | en_US | es |
| dc.publisher | Chile. Universidad Mayor | es |
| dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | es |
| dc.title | Ca2+ transfer to mitochondria: a spark of life in unexpected conditions | es |
| dc.type | Artículo o Paper | es |
| umayor.indizador | COT | es |
| umayor.politicas.sherpa/romeo | Licencia CC BY-NC-ND. Disponible en: CC BY-NC-ND | es |
| umayor.indexado | Web of Science | es |
| umayor.indexado | Scopus | es |
| umayor.indexado | PUBMED | es |
| dc.identifier.doi | 10.1080/23723556.2020.1839341 | |
| umayor.indicadores.wos-(cuartil) | Q3 | |
| umayor.indicadores.scopus-(scimago-sjr) | SJR 0.7 | |
| umayor.indicadores.scopus-(scimago-sjr) | SCIMAGO/ INDICE H: 25 H | |