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Reduced sulfation of muc5b is linked to xerostomia in patients with Sjogren syndrome
(CIENCIAS, 2008)
Objectives: MUC5B contains sulfated and sialylated oligosaccharides that sequester water required for moisturising the oral mucosa. Xerostomia, in patients with Sjogren syndrome, is generally associated with reduced ...
Matrix metalloproteinase 9 in the saliva of patients with Sjogren's syndrome: comment on the article by Goicovich et al - Reply
(CIENCIAS, 2004)
To The Editor: We would like to thank Drs. Konttinen and Azuma fortheir interesting comments concerning some of the observa-tions in our recently published article. We will focus here on 3specific issues raised, namely the ...
Involvement of specific laminins and nidogens in the active remodeling of the basal lamina of labial salivary glands from patients with Sjogren's syndrome
(CIENCIAS, 2006)
OBJECTIVE: To investigate remodeling of the basal lamina of labial salivary glands (LSGs) from patients with Sjögren's syndrome (SS) by analyzing the expression of specific components that participate in its assembly and ...
Basal lamina disorganisation of the acini and ducts of labial salivary glands from patients with Sjogren's syndrome: association with mononuclear cell infiltration
(CIENCIAS, 2006)
Objective: To study the expression of laminin and type IV collagen as biomarkers of the organisation of the basal lamina of acini and ducts in labial salivary glands from patients with Sjögren’s syndrome, and to relate ...
Increased acinar damage of salivary glands of patients with Sjogren's syndrome is paralleled by simultaneous imbalance of matrix metalloproteinase 3/tissue inhibitor of metalloproteinases 1 and matrix metalloproteinase 9/tissue inhibitor of metalloproteinases 1 ratios
(CIENCIAS, 2005)
OBJECTIVE: Previous findings in labial salivary glands (LSGs) from patients with Sjögren's syndrome (SS) suggest that increased activity and expression of matrix metalloproteinase 9 (MMP-9) and MMP-3 trigger the destruction ...
Severe alterations in expression and localisation of alpha 6 beta 4 integrin in salivary gland acini from patients with Sjogren syndrome
(CIENCIAS, 2009)
Objectives: In salivary glands from patients with Sjogren syndrome, overexpression of laminins 1 and 5 and disorganisation of the acinar basal lamina have been reported. Laminin 5 mediates association of the basal lamina ...