• Login
    View Item 
    •   DSpace Home
    • INVESTIGACIÓN
    • Artículos WOS
    • View Item
    •   DSpace Home
    • INVESTIGACIÓN
    • Artículos WOS
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    El Repositorio Institucional de la Universidad Mayor, tiene como objetivo publicar, en formato digital, todos los objetos derivados de su producción científica, académica, cultural y artística. En palabras simples es una vitrina que pone en valor su patrimonio documental.


    InformaciónInicioAcerca deFormulariosManuales

    Browse

    All of DSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    xmlui.EPerson.Navigation.loginxmlui.EPerson.Navigation.register

    Invasive fungal infections in Chile: a multicenter study of fungal prevalence and susceptibility during a 1-year period

    Thumbnail
    Date
    2004
    Author

    Diaz, María Cristina [Universidad de Chile]

    Febre, Naldy Pamela [Chile. Universidad Mayor]

    Geographic location

    Note
    Tools
    Cite
    Vea como citar este artículo

    Show full item record
    Abstract
    During the first year of an ongoing surveillance program of invasive fungal infections (IFI) a total of 130 patients (56% male) with fungal strains isolated from blood and other sterile sites were reported from 13 hospitals in Chile. Significant yeast isolates were obtained from 118 patients, and molds affected 12 patients. The main patient groups affected were neonates, children less than 1 year old and adults aged 50-79 years. All fungal bloodstream infections (BSI) were due to yeasts; 79 patients (61%) were affected. The main risk factors recorded were antibiotic therapy (76%), stay in the intensive care unit (ICU) (70%) and presence of a central venous catheter (65%). Nosocomial infections were represented in 83.5% of BSI. Overall, Candida albicans (40.8%), C. parapsilosis (13.1%), C. tropicalis (10%) and Cryptococcus neoformans (10%) were the most common species. Aspergillus fumigatus (3.1%) was the most frequent mold. C. albicans (48.1%) and C. parapsilosis (17.7%), were the most frequent agents recovered from blood. Saccharomyces cerevisiae and Trichosporon mucoides, two emerging pathogens, were also isolated. All yeasts tested were susceptible to amphotericin B with minimal inhibitory concentration (MIC) < or = 1 microg/ml. Resistance to itraconazole (MIC > or = 1 microg/ml) and fluconazole (MIC > or = 64 microg/ml) was observed in 4 and 6% of cases, respectively. C. glabrata was the least susceptible species, with 50% of isolates resistant to itraconazole and 33% resistant to fluconazole, with one strain showing combined resistance. Reduction of BSI requires greater adherence to hand-washing and related infection control guidelines.
    URI
    https://doi.org/10.1080/13693780410001657153
    http://repositorio.umayor.cl/xmlui/handle/sibum/2717
    Collections
    • Artículos WOS

    Si usted es autor(a) de este documento y NO desea que su publicación tenga acceso público en este repositorio, por favor complete el formulario aquí.


    Contact Us | Send Feedback
    Modificado por: Sistema de Bibliotecas Universidad Mayor - SIBUM
    DSpace software copyright © 2002-2018  DuraSpace
     

     



    Contact Us | Send Feedback
    Modificado por: Sistema de Bibliotecas Universidad Mayor - SIBUM
    DSpace software copyright © 2002-2018  DuraSpace