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dc.contributorSpringer-Verlages_CL
dc.contributor.authorGarcia, C. [Universidad de Chile. Facultad de Medicina]es_CL
dc.contributor.authorLagos, N [Universidad de Chile. Facultad de Medicina]es_CL
dc.contributor.authorQuiroga, G. [Pontificia Universidad Católica de Chile]es_CL
dc.contributor.authorCajigal, J. [Chile. Instituto Nacional de Deportes]es_CL
dc.contributor.authorSalazar, M. P. [Universidad de Chile. Facultad de Medicina]es_CL
dc.contributor.authorBehn, C. [Universidad de Chile. Facultad de Medicina]es_CL
dc.date.accessioned2018-09-07T14:11:41Z
dc.date.available2018-09-07T14:11:41Z
dc.date.issued2005es_CL
dc.identifier.citationAraneda, O., García, C., Lagos, N. et al. Lung oxidative stress as related to exercise and altitude. Lipid peroxidation evidence in exhaled breath condensate: a possible predictor of acute mountain sickness. Eur J Appl Physiol (2005) 95: 383. https://doi.org/10.1007/s00421-005-0047-yes_CL
dc.identifier.issnISSN 1439-6319es_CL
dc.identifier.issnESSN 1439-6327es_CL
dc.identifier.urihttps://link.springer.com/content/pdf/10.1007/s00421-005-0047-y.pdfes_CL
dc.identifier.urihttps://doi.org/10.1007/s00421-005-0047-yes_CL
dc.identifier.urihttp://repositorio.umayor.cl/xmlui/handle/sibum/2725
dc.description.abstractLung oxidative stress (OS) was explored in resting and in exercising subjects exposed to moderate and high altitude. Exhaled breath condensate (EBC) was collected under field conditions in male high-competition mountain bikers performing a maximal cycloergometric exercise at 670 m and at 2,160 m, as well as, in male soldiers climbing up to 6,125 m in Northern Chile. Malondialdehyde concentration [MDA] was measured by high-performance liquid chromatography in EBC and in serum samples. Hydrogen peroxide concentration [H2O2] was analysed in EBC according to the spectrophotometric FOX2 assay. [MDA] in EBC of bikers did not change while exercising at 670 m, but increased from 30.0±8.0 to 50.0±11.0 nmol l−1 (P<0.05) at 2,160 m. Concomitantly, [MDA] in serum and [H2O2] in EBC remained constant. On the other hand, in mountaineering soldiers, [H2O2] in EBC under resting conditions increased from 0.30±0.12 μmol l−1 at 670 m to 1.14±0.29 μmol l−1 immediately on return from the mountain. Three days later, [H2O2] in EBC (0.93 ±0.23 μmol l−1) continued to be elevated (P<0.05). [MDA] in EBC increased from 71±16 nmol l−1 at 670 m to 128±26 nmol l−1 at 3,000 m (P<0.05). Changes of [H2O2] in EBC while ascending from 670 m up to 3,000 m inversely correlated with concomitant variations in HbO2 saturation (r=−0.48, P<0.05). AMS score evaluated at 5,000 m directly correlated with changes of [MDA] in EBC occurring while the subjects moved from 670 to 3,000 m (r=0.51, P<0.05). Lung OS may constitute a pathogenic factor in AMS.es_CL
dc.description.sponsorshipEste trabajo fue financiado por: FONDECYT 1000858es_CL
dc.format.extentARTÍCULO ORIGINALes_CL
dc.language.isoenes_CL
dc.publisherCIENCIASes_CL
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chilees_CL
dc.subjectFISIOLOGÍAes_CL
dc.titleLung oxidative stress as related to exercise and altitude. Lipid peroxidation evidence in exhaled breath condensate: a possible predictor of acute mountain sicknesses_CL
dc.typeArtículo o Paperes_CL
umayor.indizadorCOTes_CL
umayor.politicas.sherpa/romeoLicencia color: VERDE C/R (Se puede archivar el pre-print y el post-print o versión de editor/PDF, el autor no puede archivar la versión del editor/PDF)--Pre-print del autor: el autor puede archivar la versión pre-print (ie la versión previa a la revisión por pares). Postcript: el autor puede archivar la versión post-print (ie la versión final posterior a la revisión por pares), Versión de editor/PDF: cross el autor no puede archivar la versión del editor/PDF, Condiciones generales: Author's pre-print on pre-print servers such as arXiv.org, Author's post-print on author's personal website immediately, Author's post-print on any open access repository after 12 months after publication, La versión de editor/PDF no puede utilizarse, La fuente editorial debe reconocerse, Debe ir enlazado a la versión de editor, Set phrase to accompany link to published version (see policy), Los artículos de algunas revistas pueden hacerse de acceso abierto mediante el pago de una tarifa adicional// Disponible en: http://www.sherpa.ac.uk/romeo/issn/1439-6319/es/es_CL
umayor.indexadoWOSes_CL
dc.identifier.doi10.1007/s00421-005-0047-yes_CL]
umayor.indicadores.wos-(cuartil)Q3es_CL
umayor.indicadores.scopus-(scimago-sjr)sin informaciónes_CL


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