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Mostrando ítems 1591-1610 de 1852
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Structure-Activity Relationships Based on 3D-QSAR CoMFA/CoMSIA and Design of Aryloxypropanol-Amine Agonists with Selectivity for the Human 3-Adrenergic Receptor and Anti-Obesity and Anti-Diabetic Profiles
(MDPI, 2018)The wide tissue distribution of the adrenergic 3 receptor makes it a potential target for the treatment of multiple pathologies such as diabetes, obesity, depression, overactive bladder (OAB), and cancer. Currently, there ... -
Study protocol and rationale of the"Cogni-action project"a cross-sectional and randomized controlled trial about physical activity, brain health, cognition, and educational achievement in schoolchildren
(BMC, 2019)BackgroundEducation and health are crucial topics for public policies as both largely determine the future wellbeing of the society. Currently, several studies recognize that physical activity (PA) benefits brain health ... -
Subcutaneous Lipoatrophy and Skin Depigmentation Secondary to TMJ Intra-Articular Corticosteroid Injection
(Royal Society Publishing, 2017)Chronic orofacial pain is a complex multidimensional experience that produces disability and impairment of normal mandibular function. Overall estimations of chronic orofacial pain prevalence are 7 to 11% of the general ... -
Subtypes of minimal residual disease and outcome for stage II colon cancer treated by surgery alone
(Cancer Intellilgence, 2020-10)Introduction: Twenty-five percent of stage II colon cancer (CC) patients relapse within 5 years due to minimal residual disease (MRD) not eliminated by surgery. We hypothesise that subtypes of MRD, defined by circulating ... -
Subtypes of minimal residual disease, association with Gleason score, risk and time to biochemical failure in pT2 prostate cancer treated with radical prostatectomy
(CANCER INTELLIGENCE LTD, 2019)Introduction: The Gleason score is a strong prognostic factor for treatment failure in pathologically organ-confined prostate cancer (pT2) treated by radical prostatectomy (RP). However, within each Gleason score, there ... -
Sudden gait perturbations elicit sex-specific neuromuscular trunk responses in persons with low back pain
(Elsevier Ltd., 2020-03)Persons with low back pain (LBP) exhibit delayed trunk muscle onset and increased co-contractions as a response to quasi-static and dynamic sudden trunk loading in comparison to back-healthy controls. Although LBP is more ... -
Suicidal ideation and attempts following nonmedical use of prescription opioids and related disorder
(Chile. Universidad Mayor, 2022-01)Background Since 1999, the rate of fatal prescription opioid overdoses and of suicides has dramatically increased in the USA. These increases, which have occurred among similar demographic groups, have led to the hypothesis ... -
Suitability of band angle indices for burned area mapping in the Maule Region (Chile)
(FRONTIERS MEDIA SA, 2023-01-04)In January 2017, 114 active fires burned throughout Chile at the same time. These fires spread quickly due to high temperatures, fast dry winds, and low vegetation water content. The fire events burned more than 570,000 ... -
Summer phyto- and bacterioplankton communities during low and high productivity scenarios in the Western Antarctic Peninsula
(SPRINGER, 2019)Phytoplankton blooms taking place during the warm season drive high productivity in Antarctic coastal seawaters. Important temporal and spatial variations exist in productivity patterns, indicating local constraints ... -
La superficie como retrato de la resistencia
(Pontificia Universidad Catolica de Chile, 2020-08)Tras el estallido social de octubre de 2019 en Chile, la arquitectura se transformó en una de sus evidencias materiales. Con el afán de resistir los posibles embates de violencia, se cubrieron las fachadas de los edificios ... -
Surface electromyographic amplitude does not identify differences in neural drive to synergistic muscles
(AMER PHYSIOLOGICAL SOC, 2018)Surface electromyographic (EMG) signal amplitude is typically used to compare the neural drive to muscles. We experimentally investigated this association by studying the motor unit (MU) behavior and action potentials in ... -
Susceptibilidad in vitro a anidulafungina en 100 cepas de especies de Candida aisladas previo a la introducción de esta equinocandina en Chile
(CIENCIAS, 2011)Los hongos, especialmente las levaduras, se han transformado en importantes patógenos oportunistas y algunos de ellos tienen o desarrollan resistencia a los antifúngicos. Para enfrentar esta problemática se han desarrollado ... -
Synaptotagmin-1 overexpression under inflammatory conditions affects secretion in salivary glands from Sjogren's syndrome patients
(ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, 2019)Sjogren's syndrome (SS) is an autoimmune exocrinopathy associated with severe secretory alterations by disruption of the glandular architecture integrity, which is fundamental for a correct function and localization of the ... -
Synergistic interactions between phenolic compounds identified in grape pomace extract with antibiotics of different classes against Staphylococcus aureus and Escherichia coli
(Public Library of Science, 2017)Synergy could be an effective strategy to potentiate and recover antibiotics nowadays useless in clinical treatments against multi-resistant bacteria. In this study, synergic interactions between antibiotics and grape ... -
Synthesis and Characterization of a 2,3-Dialkoxynaphthalene-Based Conjugated Copolymer via Direct Arylation Polymerization (DAP) for Organic Electronics
(MDPI, 2020-06-19)Poly[(5,5'-(2,3-bis(2-ethylhexyloxy)naphthalene-1,4-diyl)bis(thiophene-2,2'-diyl))-alt-(2,1,3-benzothiadiazole-4,7-diyl)] (PEHONDTBT) was synthesized for the first time and through direct arylation polymerization (DAP) for ... -
Synthesis and characterization of new spirobisindane-based poly(imide)s: Structure effects on solubility, thermal behavior, and gas transport properties
(WILEY, 2020)Two new poly(imide)s (PIs) are derived from a biphenylspirobisindane-diamine monomer and the commercial dianhydrides: 4,4 '-hexafluoroisopropyliden diphthalic anhydride (6FDA) and pyromellitic anhydride (PMDA). Using ... -
Synthesis and characterization of processable fluorinated aromatic poly (benzamide imide)s derived from cycloalkane substituted diamines, and their application in a computationally driven synthesis methodology
(ELSEVIER SCI LTD, 2019)A new set of four fluorinated aromatic poly(benzamide imide)s was synthesized with the objective of preparing condensation polymers with good processability while maintaining high chemical resistance, thermal stability and ...