• Ideal Cardiovascular Health and Incident Cardiovascular Disease Among Adults: A Systematic Review and Meta-analysis 

      Celis-Morales, Carlos A. [Univ Mayor, CIFE, Santiago, Chile]; Ramírez-Velez, Robinson; Saavedra, José M.; Lobelo, Felipe; del Pozo-Cruz, Borja; García-Hermoso, Antonio (ELSEVIER SCIENCE INC, 2018)
      Objective: To investigate the association between ideal cardiovascular health (CVH) metrics and incident cardiovascular disease (CVD) by conducting a systematic review and meta-analysis of prospective cohort studies. ...
    • Identification and Unusual Properties of the Master Regulator FNR in the Extreme Acidophile Acidithiobacillus ferrooxidans 

      Holmes, David S. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile]; Osorio, Hector; Mettert, Erin; Kiley, Patricia; Dopson, Mark; Jedlicki, Eugenia (FRONTIERS MEDIA SA, 2019)
      The ability to conserve energy in the presence or absence of oxygen provides a metabolic versatility that confers an advantage in natural ecosystems. The switch between alternative electron transport systems is controlled ...
    • Identification of Azadinium poporum (Dinophyceae) in the Southeast Pacific: Morphology, molecular phylogeny, and azaspiracid profile characterization 

      Tillmann U., Krock B., De La Iglesia R., Vásquez M.; Trefault, Nicole [Centro de Genómica y Bioinformatica, Facultad de Ciencias, Universidad Mayor, Chile]; Parada-Pozo, Genesis [Centro de Genómica y Bioinformatica, Facultad de Ciencias, Universidad Mayor, Chile] (Oxford University Press, 2017)
      Azaspiracids (AZA), a group of lipophilic phycotoxins, are produced by some species of the marine dinophycean genus Azadinium. AZA have recently been detected in shellfish from the Southeast Pacific, however, AZA-producing ...
    • Identification of c.1531C>T Pathogenic Variant in the CDH1 Gene as a Novel Germline Mutation of Hereditary Diffuse Gastric Cancer 

      Norero, Enrique; Alarcón, M. Alejandra; Hakkaart, Christopher; de Mayo, Tomás [Univ Mayor Santiago Chile, Fac Sci, Sch Med, Chile]; Mellado, Cecilia; Garrido, Marcelo; Aguayo, Gloria; Lagos, Marcela; Torres, Javiera; Calvo, Alfonso; Guilford, Parry; Corvalán, Alejandro H. (Chile. Universidad Mayor, 2019)
      Germline pathogenic variants in the CDH1 gene are a well-established cause of hereditary diffuse gastric cancer (HDGC) syndrome. The aim of this study was to characterize CDH1 mutations associated with HDGC from Chile, a ...
    • Identification of functional signatures in the metabolism of the three cellular domains of life 

      Pérez-Rueda, Ernesto {Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile]; Escobar-Turriza, Pedro; Hernández-Guerrero, Rafael; César Poot-Hernández, Augusto; Rodríguez-Vazquez, Katya; Ramírez-Prado, Jorge (PUBLIC LIBRARY SCIENCE, 2019)
      In order to identify common and specific enzymatic activities associated with the metabolism of the three cellular domains of life, the conservation and variations between the enzyme contents of Bacteria, Archaea, and ...
    • Identification of Metabolite and Lipid Profiles in a Segregating Peach Population Associated with Mealiness in Prunus persica (L.) Batsch 

      Lillo-Carmona, Victoria; Espinoza, Alonso; Rothkegel, Karin; Rubilar, Miguel; Nilo-Poyanco, Ricardo [Univ Mayor, Fac Ciencias, Escuela Biotecnol, Chile]; Pedreschi, Romina; Campos-Vargas, Reinaldo; Meneses, Claudio (MDPI Multidisciplinary Digital Publishing Institute, 2020-04)
      The peach is the third most important temperate fruit crop considering fruit production and harvested area in the world. Exporting peaches represents a challenge due to the long-distance nature of export markets. This ...
    • Identification of Modules With Similar Gene Regulation and Metabolic Functions Based on Co-expression Data 

      Pérez-Rueda, Ernesto [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile]; Galán-Vásquez, Edgardo (FRONTIERS MEDIA SA, 2019)
      Biological systems respond to environmental perturbations and to a large diversity of compounds through gene interactions, and these genetic factors comprise complex networks. In particular, a wide variety of gene co-expression ...
    • Identification of Thiotetronic Acid Antibiotic Biosynthetic Pathways by Target-directed Genome Mining 

      Tang, Xiaoyu [Estados Unidos. University of California. Institution of Oceanography]; Li, Jie [Estados Unidos. University of California San Diego. Scripps Institution of Oceanography]; Millan-Aguinaga, Natalie [Estados Unidos. University of California San Diego. Scripps Institution of Oceanography]; Zhang, Jia Jia [Estados Unidos. University of California San Diego. Scripps Institution of Oceanography]; O'Neill, Ellis C. [Estados Unidos. University of California. Scripps Institution of Oceanography]; Ugalde, Juan A [Chile. Universidad Mayor Facultad de Ciencias]; Jensen, Paul R [Estados Unidos. University of California San Diego. Scripps Institution of Oceanography]; Mantovani, Simone M. [Estados Unidos. University of California. Scripps Institution of Oceanography]; Moore, Bradley S. [Estados Unidos. University of California San Diego. Scripps Institution of Oceanography] (CIENCIAS, 2015)
      Recent genome sequencing efforts have led to the rapid accumulation of uncharacterized or "orphaned" secondary metabolic biosynthesis gene clusters (BGCs) in public databases. This increase in DNA-sequenced big data has ...
    • Idiopathic inflammatory myopathy human derived cells retain their ability to increase mitochondrial function 

      Basualto-Alarcon, Carla; Urra, Felix A.; Bozan, María Francisca; Jana, Fabián; Trangulao, Alejandra; Bevilacqua, Jorge A.; Cárdenas, J. César [Univ Mayor, Fac Sci, Lab Cellular Metab & Bioenerget, Ctr Integrat Biol, Chile] (Public Library of Science, 2020-11)
      Idiopathic Inflammatory Myopathies (IIMs) have been studied within the framework of autoimmune diseases where skeletal muscle appears to have a passive role in the illness. However, persiting weakness even after resolving ...
    • IgE serum concentration against airborne fungi in children with respiratory allergies 

      De Barros Bezerra, Geusa Felipa [Brasil. Universidade Federal do Maranhao]; Costa Haidar, Denise María [Brasil. Maternal and Child Health in Brazil]; Custodio Neto da Silva, Marcos Antonio [Brasil. Universidade Federal do Maranhao. Centro Life Sci & Hlth]; Muniz Filho, Walbert Edson [Brasil. Universidade Federal do Maranhao. Centro Life Sci & Hlth]; Dos Santos, Ramón Moura [Brasil. Universidade Federal do Maranhao. Centro Life Sci & Hlth]; Rosa, Ivone Garros [Brasil. Universidade Federal do Maranhao. Centro Life Sci & Hlth]; de Castro Viana, Graca Maria [Brasil. Universidade Federal do Maranhao. Centro Life Sci & Hlth]; Zaror, Luis [Chile. Universidad Mayor]; Soares Brandao Nascimento, Maria do Desterro [Brasil. Universidade Federal do Maranhao. Centro Life Sci & Hlth] (CIENCIAS, 2016)
      Background: To evaluate total and specific E immunoglobulin (IgE) antibody concentrations in underage subjects with respiratory allergic diseases. Methods: This study was a transversal-type study in 100 underage subjects ...
    • IL-22-expressing CD4(+)AhR(+) T lymphocytes are associated with RANKL-mediated alveolar bone resorption during experimental periodontitis 

      Cortez, Cristián [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Santiago, Chile]; Cortés, Bastián I. [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Santiago, Chile]; Vicencio, Emiliano [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Santiago, Chile]; Monasterio, Gustavo; Budini, Víctoria; Fernández, Baltasar; Castillo, Francisca; Rojas, Carolina; Alvarez, Carla; Cafferata, Emilio A.; Vernal, Rolando (WILEY, 2019)
      Background and Objective Over the past few years, the importance of interleukin-22 (IL-22) and T-helper (Th)22 lymphocytes in the pathogenesis of periodontitis has become apparent; however, there are still aspects that are ...
    • IL-22-expressing CD4(+)AhR(+) T lymphocytes are associated with RANKL-mediated alveolar bone resorption during experimental periodontitis 

      Monasterio, Gustavo; Budini, Victoria; Fernández, Baltasar; Castillo, Francisca; Rojas, Carolina; Alvarez, Carla; Cafferata, Emilio A.; Vicencio, Emiliano [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Cortés, Bastian I. [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Cortez, Cristian Andres [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Vernal, Rolando (Blackwell Munksgaard, 2019-10)
      Background and Objective Over the past few years, the importance of interleukin-22 (IL-22) and T-helper (Th)22 lymphocytes in the pathogenesis of periodontitis has become apparent; however, there are still aspects that are ...
    • Imaging the subsurface architecture in porphyry copper deposits using local earthquake tomography 

      Comte, Diana; Palma, Gisella [Univ Mayor, Escuela Geol, Chile]; Vargas, Jimena; Calle-Gardella, Daniela; Peña, Matías [Univ Mayor, Escuela Geol, Chile]; García-Fierro, Sergio [Univ Mayor, Escuela Geol, Chile]; D'Andres, Joelle; Roecker, Steven; Pichott, Sergio (NATURE PORTFOLIO, 2023-04-26)
      An essential part of the world's remaining mineral resources is expected to reside deep in the crust or under post-mineralization cover. For porphyry copper deposits, the world's primary source of Cu, Mo, and Re, identifying ...
    • Imitation of novel conspecific and human speech sounds in the killer whale (Orcinus orca). 

      Abramson, José Z. [Chile. Universidad Mayor. Facultad de Ciencias. Escuela de Medicina Veterinaria]; Hernández-Lloreda, María Victoria [España. Universidad Complutense de Madrid. Grupo UCM de Psicobiología Social, Evolutiva y Comparada]; Colmenares, Fernando [España. Universidad Complutense de Madrid. Grupo UCM de Psicobiología Social, Evolutiva y Comparada]; Aboitiz, Francisco [Chile. Pontificia Universidad Católica de Chile. Facultad de Medicina y Centro Interdisciplinario de Neurociencias. Departamento de Psiquiatría]; Call, Josep [ Reino Unido. University of St Andrews. School of Psychology and Neuroscience]; García, Lino [España. Universidad Complutense de Madrid. Facultad de Psicología. Departamento de Psicobiología] (Chile. Universidad Mayor, 2018-02-05)
      Vocal imitation is a hallmark of human spoken language, which, along with other advanced cognitive skills, has fuelled the evolution of human culture. Comparative evidence has revealed that although the ability to copy ...
    • Immediate Small-Diameter Implants as Abutments for an Overdenture in the Edentulous Atrophic Mandible: Report of Immersion Endoscopic Bone in vivo, and Histologic Bone-Implant Evaluation After 6 Months of Function 

      Lillo, Ricardo [Univ Mayor, Sci Fac, Sch Dent, Postgrad Program Oral Implantol, Santiago, Chile]; Beltran, Víctor; Weber, Benjamin; Valdivia-Gandur, Ivan; Cristina Manzanares-Céspedes, Maria; Engelke, Wilfried (SOC CHILENA ANATOMIA, 2019)
      The aim of this report was to endoscopically evaluate bone quality in vivo in the immediate installation of temporary small-diameter implants, and again after 6 months of function, through an attachments system for ...
    • Immunocytochemical and Ultrastructural Evidence Supporting That Andes Hantavirus (ANDV) Is Transmitted Person-to-Person Through the Respiratory and/or Salivary Pathways 

      Zaror, Luis [Univ Mayor, Escuela Tecnol Med, Temuco, Chile]; Pizarro, Enrique; Navarrete, Maritza; Méndez, Carolina; Mansilla, Carlos; Tapia, Mauricio; Carrasco, Cristián; Salazar, Paula; Murua, Roberto; Padula, Paula; Otth, Carola; Martin Rodríguez, Esteban (FRONTIERS MEDIA SA, 2020)
      In South America Andes hantavirus (ANDV) is hosted by the rodent Oligoryzomys longicaudatus (also known as pygmy rice rat). In humans, ANDV causes Hantavirus Pulmonary Syndrome (HPS), with a fatality rate of about 40%. ...
    • Imogolite in water: Simulating the effects of nanotube curvature on structure and dynamics 

      Gonzalez, Rafael I. [Univ Mayor, Fac Ciencias, Ctr Nanotecnol Aplicada, Chile]; Valencia, Felipe J. [Univ Mayor, Fac Estudios Interdisciplinarios, Ctr Invest DAiTA Lab, Chile]; Rojas-Nuñez, Javier; Muñoz, Francisco; Baltazar, Samuel E.; Allende, Sebastián; Rogan, José; Valdivia, Juan Alejandro; Kiwi, Miguel; Ramírez, Ricardo; Greathouse, Jeffery A. (Elsevier BV, 2019-07)
      Imogolite is a fascinating inorganic nanotube that is found in nature or synthesized in a laboratory. The synthesis process is carried out in liquid media, and leads to the formation of almost monodisperse diameter nanotubes. ...
    • IMPACT ANALYSIS OF IT USE IN LOGISTICAL COSTS OF A BRAZILIAN BEVERAGE COMPANY 

      Silva, Fabio Aquino da; Martins Oliveira, Valmir [Univ Mayor, Chile] (Chile. Universidad Mayor, 2017)
      Purpose - The main goal of this paper is to identify the impact that the use of Information Technology (IT) provides to the logistical costs of a company in the beverage industry. This research work proposes the theoretical ...
    • Impact of Dietary Lipids on Colonic Function and Microbiota: An Experimental Approach Involving Orlistat-Induced Fat Malabsorption in Human Volunteers 

      Fujio, Sayaka [Universidad de Chile. INTA]; Navarrete, Paola [Universidad de Chile. INTA]; Ugalde, Juan A. [Chile. Universidad Mayor. Centro de Genómica y Bioinformática]; Magne, Fabien [Universidad de Chile]; Carrasco-Pozo, Catalina [Universidad de Chile. Facultad de Medicina]; Tralma, Karina [Universidad de Chile. Facultad de Medicina]; Quezada, María Paz [Universidad de Chile. Facultad de Medicina]; Hurtado, Carmen [Universidad de Chile]; Covarrubias, Natalia [Universidad de Chile]; Brignardello, Jerusa [Universidad de Chile. INTA]; Henríquez, Daniela [Universidad de Chile. INTA]; Gotteland, Martin [Universidad de Chile. Facultad de Medicina] (CIENCIAS, 2016)
      OBJECTIVES: High-fat diets alter gut microbiota and barrier function, inducing metabolic endotoxemia and low-grade inflammation. Whether these effects are due to the high dietary lipid content or to the concomitant decrease ...
    • Impact of distance on mode of active commuting in Chilean children and adolescents 

      Rodríguez-Rodríguez F., Cristi-Montero C., Escobar-Gómez D., Chillón P.; Celis-Morales, Carlos [Centro de Fisiología y Biomecánica, Universidad Mayor, Chile] (MDPI Multidisciplinary Digital Publishing Institute, 2017)
      Active commuting could contribute to increasing physical activity. The objective of this study was to characterise patterns of active commuting to and from schools in children and adolescents in Chile. A total of 453 Chilean ...


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