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The Metabolomic Signature of Opa1 Deficiency in Rat Primary Cortical Neurons Shows Aspartate/Glutamate Depletion and Phospholipids Remodeling
(NATURE PUBLISHING GROUP, 2019)Pathogenic variants of OPA1, which encodes a dynamin GTPase involved in mitochondrial fusion, are responsible for a spectrum of neurological disorders sharing optic nerve atrophy and visual impairment. To gain insight on ... -
The Microbial Composition in Circumneutral Thermal Springs from Chignahuapan, Puebla, Mexico Reveals the Presence of Particular Sulfur-Oxidizing Bacterial and Viral Communities
(MDPI AG, 2020-11)Terrestrial thermal springs are widely distributed globally, and these springs harbor a broad diversity of organisms of biotechnological interest. In Mexico, few studies exploring this kind of environment have been described. ... -
The Mitochondrial Unfolded Protein Response: A Hinge Between Healthy and Pathological Aging
(Frontiers Media S.A., 2020-09)Aging is the time-dependent functional decline that increases the vulnerability to different forms of stress, constituting the major risk factor for the development of neurodegenerative diseases. Dysfunctional mitochondria ... -
The necroptosis pathway and its role in age-related neurodegenerative diseases: will it open up new therapeutic avenues in the next decade?
(Taylor and Francis Ltd., 2020-07)Introduction: Necroptosis is a programmed form of necrotic cell death. Growing evidence demonstrates that necroptosis contributes to cell demise in different pathological conditions including age-dependent neurodegenerative ... -
The negative effect of lianas on tree growth varies with tree species and seasonPalavras-chave
(Wiley-Blackwell, 2020-05)Lianas reduce tree growth, reproduction, and survival in tropical forests. Liana competition can be particularly intense in isolated forest fragments, where liana densities are high, and thus, host tree infestation is ... -
THE ORGANIZATIONAL CULTURE AND VALUES ALIGNMENT MANAGEMENT IMPORTANCE FOR SUCCESSFUL BUSINESS
(Chile. Universidad Mayor, 2017)The main objective of this study was to carry out an organizational culture diagnosis in a shipyard, verifying the alignment degree between personal and organizational values. For data collection, a structured questionnaire ... -
The origin and emplacement of Domo Tinto, Guallatiri volcano, Northern Chile.
(CIENCIAS, 2014)El volcán Guallatiri (18°25'S, 69°05'W) es un edificio volcánico ubicado en el Altiplano del norte de Chile, cercano a la frontera con Bolivia. Este volcán, construido en el Pleistoceno-Holoceno en el extremo sur de la ... -
The p75(NTR) neurotrophin receptor is required to organize the mature neuromuscular synapse by regulating synaptic vesicle availability
(BMC, 2019)The coordinated movement of organisms relies on efficient nerve-muscle communication at the neuromuscular junction. After peripheral nerve injury or neurodegeneration, motor neurons and Schwann cells increase the expression ... -
The Phylogeographic Diversity of EBV and Admixed Ancestry in the Americas-Another Model of Disrupted Human-Pathogen Co-Evolution
(MDPI, 2019)Epstein-Barr virus (EBV) is an etiological agent for gastric cancer with significant worldwide variations. Molecular characterizations of EBV have shown phylogeographical variations among healthy populations and in ... -
The positive side of a negative reference: The delay between linguistic processing and common ground
(The Royal Society, 2017)Interlocutors converge on names to refer to entities. For example, a speaker might refer to a novel looking object as the jellyfish and, once identified, the listener will too. The hypothesized mechanism behind such ... -
The power of a control qubit in weak measurements
(NATURE PUBLISHING GROUP, 2017)In the late 80 s, a curious effect suggested by Aharanov et al. was found to lead to an anomalous amplification based on quantum measurements of weakly coupled systems. In this paper, we investigate the quantum control of ... -
The process of connectivity loss during habitat fragmentation and their consequences on population dynamics
(ELSEVIER SCIENCE BV, 2018)Understanding the processes and consequences of habitat fragmentation is highly relevant since it represents a serious threat to biodiversity. However, fragmentation includes several facets that are difficult to dissect, ... -
The Profit Motive in the Crime of Migrant Smuggling: Critical Analysis of European Legislation
(UNIV REPUBLICA, FAC DERECHO, 2019)The present paper critically analyzes the European legislation on smuggling of migrants. According to the author's opinion, the communitarian legislator and the majority of the European countries have confused this specific ... -
The protein architecture in Bacteria and Archaea identifies a set of promiscuous and ancient domains
(Public Library of Science, 2019-12-19)In this work, we describe a systematic comparative genomic analysis of promiscuous domains in genomes of Bacteria and Archaea. A quantitative measure of domain promiscuity, the weighted domain architecture score (WDAS), ... -
The racialization of immigrants in Canada - a historical investigation how race still matters
(EMERALD GROUP PUBLISHING LTD, 2019)Purpose This paper aims to investigate the discursive ways in which racialization affects the integration process of immigrants in present-day Canada. By drawing on a historical analysis, this paper shows how race continues ...