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Highly porous tungsten for plasma-facing applications in nuclear fusion power plants: a computational analysis of hollow nanoparticles
(IOP Publishing Ltd., 2020-09)
Plasma-facing materials (PFMs) for nuclear fusion, either in inertial confinement fusion (ICF) or in magnetic confinement fusion (MCF) approaches, must withstand extremely hostile irradiation conditions. Mitigation strategies ...
Idiopathic inflammatory myopathy human derived cells retain their ability to increase mitochondrial function
(Public Library of Science, 2020-11)
Idiopathic Inflammatory Myopathies (IIMs) have been studied within the framework of autoimmune diseases where skeletal muscle appears to have a passive role in the illness. However, persiting weakness even after resolving ...
Identification of Metabolite and Lipid Profiles in a Segregating Peach Population Associated with Mealiness in Prunus persica (L.) Batsch
(MDPI Multidisciplinary Digital Publishing Institute, 2020-04)
The peach is the third most important temperate fruit crop considering fruit production and harvested area in the world. Exporting peaches represents a challenge due to the long-distance nature of export markets. This ...
Nicotinamide, a Poly [ADP-Ribose] Polymerase 1 (PARP-1) Inhibitor, as an Adjunctive Therapy for the Treatment of Alzheimer's Disease
(Frontiers Media S.A., 2020-08)
Nicotinamide (vitamin B3) is a key component in the cellular production of Nicotinamide Adenine Dinucleotide (NAD) and has long been associated with neuronal development, survival and death. Numerous data suggest that ...
In vitropropagation ofLeptocarpha rivularis, a native medicinal plant
(Springer New York, 2020-12)
Leptocarpha rivularis, commonly known as "palo negro", is a species of the Astereaceae family, endemic in the forests of Southern Chile. The extracts of this plant have medicinal properties attributable to its secondary ...
Implications of Selective Autophagy Dysfunction for ALS Pathology
(MDPI Multidisciplinary Digital Publishing Institute, 2020-02)
Amyotrophic lateral sclerosis (ALS) is a lethal neurodegenerative disorder that progressively affects motor neurons in the brain and spinal cord. Due to the biological complexity of the disease, its etiology remains unknown. ...
Perception and legitimation in the face of socioecological inequalities in contemporary Chile
(Latin American Studies Association, 2020)
This article analyzes the perceptions about and legitimation of inequalities in the case of Chile, focusing on the socioecological dimension. It shows the results of a four-year qualitative study carried out in five cases ...
New Poly(imide)s Bearing Alkyl Side-Chains: A Study on the Impact of Size and Shape of Lateral Groups on Thermal, Mechanical, and Gas Transport Properties
(MDPI AG, 2020-07)
A set of five new aromatic poly(imide)s (PIs) incorporating pendant acyclic alkyl moieties were synthesized. The difference among them was the length and bulkiness of the pendant group, which comprises of linear alkyl ...
Interleukin-17-induced neutrophil extracellular traps mediate resistance to checkpoint blockade in pancreatic cancer
(Rockefeller University Press, 2020-12)
Pancreatic ductal adenocarcinoma (PDAC) remains a lethal malignancy with an immunosuppressive microenvironment that is resistant to most therapies. IL17 is involved in pancreatic tumorigenesis, but its role in invasive ...
Neuronal HIF-1 alpha in the nucleus tractus solitarius contributes to ventilatory acclimatization to hypoxia
(Wiley-Blackwell Publishing Ltd, 2020-05)
We hypothesized that hypoxia inducible factor 1 alpha (HIF-1 alpha) in CNS respiratory centres is necessary for ventilatory acclimatization to hypoxia (VAH); VAH is a time-dependent increase in baseline ventilation and the ...