• Identification and Unusual Properties of the Master Regulator FNR in the Extreme Acidophile Acidithiobacillus ferrooxidans 

      Holmes, David S. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile]; Osorio, Hector; Mettert, Erin; Kiley, Patricia; Dopson, Mark; Jedlicki, Eugenia (FRONTIERS MEDIA SA, 2019)
      The ability to conserve energy in the presence or absence of oxygen provides a metabolic versatility that confers an advantage in natural ecosystems. The switch between alternative electron transport systems is controlled ...
    • Improved ontology for eukaryotic single-exon coding sequences in biological databases 

      Holmes, David S. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile]; Jorquera, Roddy; González, Carolina; Clausen, Philip; Petersen, Bent (OXFORD UNIV PRESS, 2018)
      Efficient extraction of knowledge from biological data requires the development of structured vocabularies to unambiguously define biological terms. This paper proposes descriptions and definitions to disambiguate the term ...


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