Browsing Centro de Investigación en Genómica y Bioinformática (CGB) by Subject "Multidisciplinary Sciences"
Now showing items 1-5 of 5
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Identification of functional signatures in the metabolism of the three cellular domains of life
(PUBLIC LIBRARY SCIENCE, 2019)In order to identify common and specific enzymatic activities associated with the metabolism of the three cellular domains of life, the conservation and variations between the enzyme contents of Bacteria, Archaea, and ... -
Pleione: A tool for statistical and multi-objective calibration of Rule-based models
(NATURE PUBLISHING GROUP, 2019)Mathematical models based on Ordinary Differential Equations (ODEs) are frequently used to describe and simulate biological systems. Nevertheless, such models are often difficult to understand. Unlike ODE models, Rule-Based ... -
RIP-MD: a tool to study residue interaction networks in protein molecular dynamics
(PEERJ INC, 2018)Protein structure is not static; residues undergo conformational rearrangements and, in doing so, create, stabilize or break non-covalent interactions. Molecular dynamics (MD) is a technique used to simulate these movements ... -
Signal peptide recognition in Trypanosoma cruzi GP82 adhesin relies on its localization at protein N-terminus
(NATURE PUBLISHING GROUP, 2019)Trypanosoma cruzi, the causative agent of Chagas disease, has a dense coat of GPI-anchored virulence factors. T. cruzi GPI-anchored adhesin GP82 is encoded by a repertoire of transcripts containing several in-frame initiation ... -
Whole Genome Sequence, Variant Discovery and Annotation in Mapuche-Huilliche Native South Americans
(NATURE PUBLISHING GROUP, 2019)Whole human genome sequencing initiatives help us understand population history and the basis of genetic diseases. Current data mostly focuses on Old World populations, and the information of the genomic structure of Native ...