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Identification of Modules With Similar Gene Regulation and Metabolic Functions Based on Co-expression Data
(FRONTIERS MEDIA SA, 2019)
Biological systems respond to environmental perturbations and to a large diversity of compounds through gene interactions, and these genetic factors comprise complex networks. In particular, a wide variety of gene co-expression ...
The protein architecture in Bacteria and Archaea identifies a set of promiscuous and ancient domains
(Public Library of Science, 2019-12-19)
In this work, we describe a systematic comparative genomic analysis of promiscuous domains in genomes of Bacteria and Archaea. A quantitative measure of domain promiscuity, the weighted domain architecture score (WDAS), ...