Now showing items 1301-1301 of 1301

    • β8 integrin expression and activation of tgf-β by intestinal dendritic cells are determined by both tissue microenvironment and cell lineage 

      Boucard-Jourdin, Mathilde [Université de Lyon. Centre International de Recherche en Infectiologie]; Kugler, David [Benaroya Research Institute, Seattle]; Endale Ahanda, Marie Laure [Université de Lyon. Centre International de Recherche en Infectiologie]; This, Sébastien [Université de Lyon. Centre International de Recherche en Infectiologie]; De Calisto, Jaime [Chile. Universidad Mayor. Facultad de Ciencias. Centro de Genómica y Bioinformática]; Zhang, Ailiang [University of Edinburgh. Queen's Medical Research Institute]; Mora, J. Rodrigo [Massachusetts General Hospital, Boston]; Stuart, Lynda M. [Benaroya Research Institute, Seattle]; Savill John [University of Edinburgh. Queen's Medical Research Institute]; Lacy-Hulbert, Adam [Benaroya Research Institute, Seattle]; Paidassi, Helena [Université de Lyon. Centre International de Recherche en Infectiologie] (Facultad de Ciencias, 2016)
      Activation of TGF-β by dendritic cells (DCs) expressing αvβ8 integrin is essential for the generation of intestinal regulatory T cells (Tregs) that in turn promote tolerance to intestinal Ags. We have recently shown that ...