ListarINVESTIGACIÓN por tema "CIENCIAS BIOLÓGICAS"
Mostrando ítems 1-16 de 16
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A comparative performance analysis of total PSA, percentage free PSA, PSA velocity, and PSA density versus the detection of primary circulating prostate cells in predicting initial prostate biopsy findings in chilean men
(CIENCIAS, 2014)Introduction. PSA parameters have been used in an attempt to improve the diagnostic yield of prostate screening tests; the detection of primary malignant circulating prostate cells (CPCs) may improve the diagnostic yield ... -
ALS-linked protein disulfide isomerase variants cause motor dysfunction
(CIENCIAS, 2016)Disturbance of endoplasmic reticulum (ER) proteostasis is a common feature of amyotrophic lateral sclerosis (ALS). Protein disulfide isomerases (PDIs) are ER foldases identified as possible ALS biomarkers, as well as ... -
Altered potassium channel distribution and composition in myelinated axons suppresses hyperexcitability following injury
(CIENCIAS, 2016)Neuropathic pain following peripheral nerve injury is associated with hyperexcitability in damaged myelinated sensory axons, which begins to normalise over time. We investigated the composition and distribution of ... -
Biogeographic origin and thermal acclimation interact to determine survival and hsp90 expression in Drosophila species submitted to thermal stress
(CIENCIAS, 2012)The relationship between thermal tolerance and environmental conditions has been extensively studied in Drosophila. However, comparisons of thermal tolerance of laboratory-bred flies derived from distinct geographic locations ... -
Comparative study of mouthparts of three species of horse flies of the tribe Pangoniini of Chilean distribution (Diptera: Tabanidae)
(CIENCIAS, 2004)Mouthparts of 3 species representing Esenbeckia Rondani, Protodasyapha Enderlein, and Veprius Rondani of the tribe Pangoniini were examined by scanning electron microscopy (SEM), and their structures are herein described. ... -
Evolving in thin air - Lessons from the llama fetus in the altiplano
(CIENCIAS, 2007)Compared with lowland species, fetal life for mammalian species whose mothers live in high altitude is demanding. For instance, fetal llamas have to cope with the low fetal arterial PO2 of all species, but also the likely ... -
FBN-1, a fibrillin-related protein, is required for resistance ofthe epidermis to mechanical deformation during c. Elegans embryogenesis
(CIENCIAS, 2015)During development, biomechanical forces contour the body and provide shape to internal organs. Using genetic and molecular approaches in combination with a FRET-based tension sensor, we characterized a pulling force exerted ... -
Guide to Scientific Crowdfunding
(CIENCIAS, 2016)Crowdfunding represents an attractive new option for funding research projects, especially for students and early-career scientists or in the absence of governmental aid in some countries. The number of successful ... -
Marine photosynthetic eukaryotes in polar systems: Unveiling phytoplankton diversity and composition in Antarctic waters
(CIENCIAS, 2012)Las aguas antárticas son un ambiente marino peculiar debido principalmente a las fuertes variaciones estacionales a las que están sujetos varios parámetros, como disponibilidad de luz y temperatura. Al igual que en todas ... -
Mitochondria in the Aging Muscles of Flies and Mice: New Perspectives for Old Characters
(CIENCIAS, 2016)Sarcopenia is the loss of muscle mass accompanied by a decrease in muscle strength and resistance and is the main cause of disability among the elderly. Muscle loss begins long before there is any clear physical impact in ... -
Nuevo varamiento masivo de orca falsa, Pseudorca crassidens, en el Estrecho de Magallanes, Chile
(CIENCIAS, 2015)We report the mass stranding of 46 false killer whales in the Strait of Magellan in February 2013. We present observation-based information about body size, sex, dental formula and necropsies. Sexual dimorphism in body ... -
Origin of axonal proteins: Is the axon-schwann cell unit a functional syncytium?
(CIENCIAS, 2016)The structural homeostasis is challenging for neurons, whose axons extend up to meters in large animals, and the axoplasmic mass reaches over a thousand times that of the cell body. Thus, the protein demand may overcome ... -
Ostreococcus Tauri Luminescent Reporter Lines as Biosensors for Detecting Pollution From Copper-Mine Tailing Effluents in Coastal Environments
(Facultad de Ciencias, 2018)Phytoplankton cells are excellent biosensors for environmental monitoring and toxicity assessments in different natural systems. Green algae, in particular, appear to be more responsive to copper (Cu) disturbances. This ... -
Recombinant lactic acid bacteria as delivery vectors of heterologous antigens: the future of vaccination?
(CIENCIAS, 2015)Lactic acid bacteria (LABs) are good candidates for the development of new oral vaccines and are attractive alternatives to attenuated pathogens. This review focuses on the use of wild-type and recombinant lactococci and ... -
The expression of heterologous MAM-7 in Lactobacillus rhamnosus reduces its intrinsic capacity to inhibit colonization of pathogen Vibrio parahaemolyticus in vitro.
(CIENCIAS, 2016)BACKGROUND: Vibrio parahaemolyticus (V. parahaemolyticus) is a Gram-negative, halophilic bacterium recognized as one of the most important foodborne pathogen. When ingested, V. parahaemolyticus causes a self-limiting illness ... -
Variation in coastal Antarctic microbial community composition at sub-mesoscale: spatial distance or environmental filtering?
(CIENCIAS, 2016)Spatial environmental heterogeneity influences diversity of organisms at different scales. Environmental filtering suggests that local environmental conditions provide habitat-specific scenarios for niche requirements, ...