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Coagulation Factor Xa Promotes Solid Tumor Growth, Experimental Metastasis and Endothelial Cell Activation
(MDPI, 2019)
Hypercoagulable state is linked to cancer progression; however, the precise role of the coagulation cascade is poorly described. Herein, we examined the contribution of a hypercoagulative state through the administration ...
Nanopore Sequencing Significantly Improves Genome Assembly of the Protozoan Parasite Trypanosoma cruzi
(OXFORD UNIV PRESS, 2019)
Chagas disease was described by Carlos Chagas, who first identified the parasite Trypanosoma cruzi from a 2-year-old girl called Berenice. Many T. cruzi sequencing projects based on short reads have demonstrated that genome ...
Adherence to physical activity recommendations across age categories: Findings from the 2009-2010 Chilean National Health Survey
(SOC CHILENA NUTRICION, BROMATOLOGIA & TOXICOLOGIA, 2019)
Although physical activity (PA) is a protective factor against non-communicable diseases, there is an important proportion of the population who do not meet PA guidelines. Our aim was to investigate how adherence to PA ...
c-Jun N-terminal kinase (JNK)-dependent internalization and Rab5-dependent endocytic sorting mediate long-distance retrograde neuronal death induced by axonal BDNF-p75 signaling
(NATURE PUBLISHING GROUP, 2019)
During the development of the sympathetic nervous system, signals from tropomyosin-related kinase receptors (Trks) and p75 neurotrophin receptors (p75) compete to regulate survival and connectivity. During this process, ...
Cognitive impairment in heart failure is associated with altered Wnt signaling in the hippocampus
(IMPACT JOURNALS LLC, 2019)
Age represents the highest risk factor for death due to cardiovascular disease. Heart failure (HF) is the most common cardiovascular disease in elder population and it is associated with cognitive impairment (CI), diminishing ...
Oral contraceptive use and depression among adolescents
(ELSEVIER SCIENCE INC, 2019)
Purpose: Depression is a prevalent health problem affecting U.S. women. Oral contraceptive pills (OCPs) are commonly used for pregnancy prevention, and evidence is mixed regarding any increased risk for incident depression ...
Rostral ventrolateral medullary catecholaminergic neurones mediate irregular breathing pattern in volume overload heart failure rats
(WILEY, 2019)
Key points A strong association between disordered breathing patterns, elevated sympathetic activity, and enhanced central chemoreflex drive has been shown in experimental and human heart failure (HF). The aim of this study ...
Prescription drug monitoring programs operational characteristics and fatal heroin poisoning
(ELSEVIER, 2019)
Background: Prescription drug monitoring programs (POMP), by reducing access to prescribed opioids (POs), may contribute to a policy environment in which some people with opioid dependence are at increased risk for ...
Neurocognitive Disorders in Heart Failure: Novel Pathophysiological Mechanisms Underpinning Memory Loss and Learning Impairment
(SPRINGER, 2019)
Heart failure (HF) is a major public health issue affecting more than 26 million people worldwide. HF is the most common cardiovascular disease in elder population; and it is associated with neurocognitive function decline, ...
The Term Muscle and its Internal Coherence: A Suggestion to Terminologia Histologica
(SOC CHILENA ANATOMIA, 2019)
Terminologia Histologica (TH) was prepared following the indications of the International Committee on Anatomical Terminology (FIPAT), however, it is not exempt from errors and inconsistencies. the above information is ...