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Gadolinium Chloride Rescues Niemann-Pick Type C Liver Damage
(MDPI, 2018)
Niemann-Pick type C (NPC) disease is a rare neurovisceral cholesterol storage disorder that arises from loss of function mutations in the NPC1 or NPC2 genes. Soon after birth, some patients present with an aggressive ...
Improved ontology for eukaryotic single-exon coding sequences in biological databases
(OXFORD UNIV PRESS, 2018)
Efficient extraction of knowledge from biological data requires the development of structured vocabularies to unambiguously define biological terms. This paper proposes descriptions and definitions to disambiguate the term ...
Structure-Activity Relationships Based on 3D-QSAR CoMFA/CoMSIA and Design of Aryloxypropanol-Amine Agonists with Selectivity for the Human 3-Adrenergic Receptor and Anti-Obesity and Anti-Diabetic Profiles
(MDPI, 2018)
The wide tissue distribution of the adrenergic 3 receptor makes it a potential target for the treatment of multiple pathologies such as diabetes, obesity, depression, overactive bladder (OAB), and cancer. Currently, there ...
A highly stable black phosphorene nanocomposite for voltammetric detection of clenbuterol
(SPRINGER WIEN, 2018)
A nanocomposite was prepared from graphene-like two-dimensional black phosphorene (BP, an allotrope of phosphorus) and nafion (Nf) treated with isopropanol (IP). A glassy carbon electrode (GCE) modified with this nanocomposite ...
Coherent population trapping with a controlled dissipation: applications in optical metrology
(IOP PUBLISHING LTD, 2018)
We analyze the properties of a pulsed coherent population trapping protocol that uses a controlled decay from the excited state in a Lambda-level scheme. We study this problem analytically and numerically and find regimes ...
Highly efficient cooling of mechanical resonator with square pulse drives
(OPTICAL SOC AMER, 2018)
Ground state cooling of mechanical resonator is a way to generate macroscopic quantum states. Here we present a study of optomechanical cooling under the drive of square pulses without smooth profile. By illustrating the ...
Ground-state cooling of a nanomechanical oscillator with N spins
(AMER PHYSICAL SOC, 2018)
It is typical of modern quantum technologies employing nanomechanical oscillators to demand few mechanical quantum excitations, for instance, to prolong coherence times of a particular task or to engineer a specific ...
Optical qubit generation via atomic postselection in a Ramsey interferometer
(IOP PUBLISHING LTD, 2018)
We propose a realizable experimental scheme to prepare a superposition of the vacuum and one-photon states using a typical cavity QED-setup. This is different from previous schemes, where the superposition state of the ...
Prelimary Results of the Reaction of Cyclotrimerization of Phenylacetylene [2+2+2] Catalyzed by [(Cp*)Co(Indene)] Complex
(Sociedad Chilena de Química, 2018-03)
This work describes the catalytic study of [(Cp*)Co(Ind)] (with Cp*- pentamethylcyclopentadienyl, Ind = Indenyl, (C9H7)) complex in cyclotrimerization of phenylacetylene. From the cylcotrimerization reaction was possible ...
One-step coelectrodeposition-assisted layer-by-layer assembly of gold nanoparticles and reduced graphene oxide and its self-healing three-dimensional nanohybrid for an ultrasensitive DNA sensor
(ROYAL SOC CHEMISTRY, 2018-01-21)
A layer-by-layer (LBL) assembly was employed for preparing multilayer thin films with a controlled architecture and composition. In this study, we report the one-step coelectrodeposition-assisted LBL assembly of both gold ...