Artículos WOS: Envíos recientes
Mostrando ítems 1541-1560 de 1852
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Transcriptomics reveals a cross-modulatory effect between riboflavin and iron and outlines responses to riboflavin biosynthesis and uptake in Vibrio cholerae
(NATURE PUBLISHING GROUP, 2018)Vibrio cholerae, a pandemic diarrheagenic bacterium, is able to synthesize the essential vitamin riboflavin through the riboflavin biosynthetic pathway (RBP) and also to internalize it through the RibN importer. In bacteria, ... -
Temporal trend of hospital discharges due to infectious diseases in Chile, 2004-2014
(SOC CHILENA INFECTOLOGIA, 2018)Background: Infectious diseases are important causes of burden of illness and mortality. Aim: To describe the temporal trends of hospital discharges due to infectious in Chile from 2004 to 2014. Methods: Descriptive study. ... -
The Evil and the Dionysian Machine: the literature through Foucault, Deleuze and Baudrillard
(UNIV SERENA, FAC HUMANIDADES, 2018)The article proposes that the literature configures spaces where the thought of the outside emerges: a way of thinking that opposes the notions of interiority, common sense and good sense. For this, the categories of ... -
Video surveillance and privacy: Considerations about the cases Blimps and Drones
(UNIV CHILE, FAC DERECHO, 2018)This article analyzes the conflicting relationship between video surveillance practices and the right to privacy. With this purpose, two recent cases resolved by the High Courts of Justice are reviewed. After identifying ... -
In Memoriam Christopher Gregory Weeramantry 1926-2017, Lawyer
(UNAM, INST INVESTIGACIONES JURIDICAS, 2018) -
In Memoriam Sir Elihu Lauterpacht 1928-2017, Lawyer
(UNAM, INST INVESTIGACIONES JURIDICAS, 2018) -
Linked homozygous BMPR1B and PDHA2 variants in a consanguineous family with complex digit malformation and male infertility
(NATURE PUBLISHING GROUP, 2018)In affected members of a consanguineous family, a syndrome, which is concurrence of set of medical signs, is often observed and commonly assumed to have arisen from pleiotropy, i.e., the phenomenon of a single gene variant ... -
Vitamin D Increases A beta 140 Plasma Levels and Protects Lymphocytes from Oxidative Death in Mild Cognitive Impairment Patients
(BENTHAM SCIENCE PUBL LTD, 2018)Background: Mild cognitive impairment (MCI) has an increased rate of progression to dementia. Alterations of some metabolic factors, such as deficiency of vitamin D, are a risk factor for cognitive deterioration. Vitamin ... -
Axonal degeneration induced by glutamate excitotoxicity is mediated by necroptosis
(COMPANY BIOLOGISTS LTD, 2018)Neuronal excitotoxicity induced by glutamate leads to cell death and functional impairment in a variety of central nervous system pathologies. Glutamate-mediated excitotoxicity triggers neuronal apoptosis in the cell soma ... -
Fishing forward and reverse: Advances in zebrafish phenomics
(ELSEVIER, 2018)Understanding how the genome instructs the phenotypic characteristics of an organism is one of the major scientific endeavors of our time. Advances in genetics have progressively deciphered the inheritance, identity and ... -
Homozygous mutation in CEP19, a gene mutated in morbid obesity, in Bardet-Biedl syndrome with predominant postaxial polydactyly
(BMJ PUBLISHING GROUP, 2018)Background Bardet-Biedl syndrome (BBS) is a ciliopathy with extensive phenotypic variability and genetic heterogeneity. We aimed to discover the gene mutated in a consanguineous kindred with multiple cases of a BBS phenotype. ... -
The inhibition of CTGF/CCN2 activity improves muscle and locomotor function in a murine ALS model
(OXFORD UNIV PRESS, 2018)Amyotrophic lateral sclerosis (ALS) is a devastating adult-onset progressive neurodegenerative disease characterized by upper and lower motoneuron degeneration. A total of 20% of familial ALS (fALS) cases are explained by ... -
Outside in: Unraveling the Role of Neuroinflammation in the Progression of Parkinson's Disease
(FRONTIERS MEDIA SA, 2018)Neuroinflammation is one of the most important processes involved in the pathogenesis of Parkinson's disease (PD). The current concept of neuroinflammation comprises an inflammation process, which occurs in the central ... -
Mitochondria and Calcium Regulation as Basis of Neurodegeneration Associated With Aging
(FRONTIERS MEDIA SA, 2018)Age is the main risk factor for the onset of neurodegenerative diseases. A decline of mitochondrial function has been observed in several age-dependent neurodegenerative diseases and may be a major contributing factor in ... -
IRE1 alpha governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A
(NATURE PUBLISHING GROUP, 2018)Maintenance of endoplasmic reticulum (ER) proteostasis is controlled by a signalling network known as the unfolded protein response (UPR). Here, we identified filamin A as a major binding partner of the ER stress transducer ... -
Endoplasmic reticulum stress leads to accumulation of wild-type SOD1 aggregates associated with sporadic amyotrophic lateral sclerosis
(NATL ACAD SCIENCES, 2018)Abnormal modifications to mutant superoxide dismutase 1 (SOD1) are linked to familial amyotrophic lateral sclerosis (fALS). Misfolding of wild-type SOD1 (SOD1(WT)) is also observed in postmortem tissue of a subset of ... -
Unraveling the role of motoneuron autophagy in ALS
(TAYLOR & FRANCIS INC, 2018)In recent years, the role of autophagy in the pathogenesis of most neurodegenerative diseases has transitioned into a limbo of protective or detrimental effects. Genetic evidence indicates that mutations in autophagy-regulatory ... -
Terapia combinada con miel de Ulmo (Eucryphia cordifolia) y ácido ascórbico en úlceras venosas
(CIENCIAS, 2015)Objetivo: evaluar el efecto clínico del tratamiento con miel de Ulmo tópico asociado a ácido ascórbico oral en pacientes portadores de úlceras venosas. Método: estudio cuantitativo descriptivo longitudinal. Durante el ... -
Un caso de queratitis micótica por Fusarium solani en Valdivia, Chile
(CIENCIAS, 2015)Antecedentes: La queratitis micótica es una de las principales infecciones oculares. Se necesita un tratamiento específico que depende de la naturaleza del microorganismo infectante. Su pronóstico suele ser grave y depende ... -
Transmisión de infecciones por endoscopios y broncoscopios
(CIENCIAS, 2014)Este artículo corresponde a un comentario en la sección Revista de Revistas, en que se analiza el artículo: Transmission of infection by flexible gastrointestinal endoscopy and bronchoscopy, de los autores Kovaleva J, ...