Mostrando ítems 861-880 de 1852

    • Boldine inhibits the alveolar bone resorption during ligature-induced periodontitis by modulating the Th17/Treg imbalance 

      Cafferata, Emilio A.; Castro-Saavedra, Sebastián; Fuentes-Barros, Gonzalo; Melgar-Rodriguez, Samanta; Rivera, Felipe; Carvajal, Paola; Hernández, Marcela; Cortés, Bastian, I [Centro de Biología Integrativa, Facultad de Ciencias, Universidad Mayor, Chile]; Cortez, Cristian [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Cassels, Bruce K.; Vernal, Rolando (Chile. Universidad Mayor, 2020-06)
      Background During periodontitis, tooth-supporting alveolar bone is resorbed when there is an increased expression of the pro-osteolytic factor termed receptor activator of nuclear factor kappa B ligand (RANKL), which is ...
    • Aggregatibacter actinomycetemcomitans Induces Autophagy in Human Junctional Epithelium Keratinocytes 

      Cordero, Esteban M. [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Cortes, Bastian I. [Centro de Biología Intergrativa, Facultad de Ciencias, Universidad Mayor, Chile]; Palominos, Sebastián [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Parra, Pedro [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Mella, Tania [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Henrríquez, Constanza [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Salazar, Nelda [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Monasterio, Gustavo; Cafferata, Emilio A.; Murgas, Paola [Centro de Biología Intergrativa, Facultad de Ciencias, Universidad Mayor, Chile]; Vernal, Rolando; Cortez, Cristian Andres [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile] (MDPI, 2020-05)
      The adverse environmental conditions found in the periodontium during periodontitis pathogenesis stimulate local autophagy responses, mainly due to a continuous inflammatory response against the dysbiotic subgingival ...
    • Nutrient dose-responsive transcriptome changes driven by Michaelis Menten kinetics underlie plant growth rates 

      Swift, Joseph; Alvarez, Jose M. [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Araus, Viviana; Gutiérrez, Rodrigo A.; Coruzzi, Gloria M. (National Academy of Sciences, 2020-06-09)
      An increase in nutrient dose leads to proportional increases in crop biomass and agricultural yield. However, the molecular underpinnings of this nutrient dose-response are largely unknown. To investigate, we assayed changes ...
    • Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade 

      Alvarez, Jose M. [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Schinke, Anna-Lena; Brooks, Matthew D.; Pasquino, Angelo; Leonelli, Lauriebeth; Varala, Kranthi; Safi, Alaeddine; Krouk, Gabriel; Krapp, Anne; Coruzzi, Gloria M. (Nature Publishing Group, 2020-03-02)
      Dynamic reprogramming of gene regulatory networks (GRNs) enables organisms to rapidly respond to environmental perturbation. However, the underlying transient interactions between transcription factors (TFs) and genome-wide ...
    • A balancing act: how plants integrate nitrogen and water signals 

      Araus, Viviana; Swift, Joseph; Alvarez, Jose M. [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Henry, Amelia; Coruzzi, Gloria M. (Oxford University Press, 2020-07-25)
      Nitrogen (N) and water (W) are crucial inputs for plant survival as well as costly resources for agriculture. Given their importance, the molecular mechanisms that plants rely on to signal changes in either N or W status ...
    • IL-22-expressing CD4(+)AhR(+) T lymphocytes are associated with RANKL-mediated alveolar bone resorption during experimental periodontitis 

      Monasterio, Gustavo; Budini, Victoria; Fernández, Baltasar; Castillo, Francisca; Rojas, Carolina; Alvarez, Carla; Cafferata, Emilio A.; Vicencio, Emiliano [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Cortés, Bastian I. [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Cortez, Cristian Andres [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Vernal, Rolando (Blackwell Munksgaard, 2019-10)
      Background and Objective Over the past few years, the importance of interleukin-22 (IL-22) and T-helper (Th)22 lymphocytes in the pathogenesis of periodontitis has become apparent; however, there are still aspects that are ...
    • Engineering a single-chain antibody against Trypanosoma cruzi metacyclic trypomastigotes to block cell invasion 

      Kalempa Demeu, Lara Maria; Soares, Rodrigo Jahn; Miranda, Juliana Severo; Pacheco-Lugo, Lisandro A.; Oliveira, Kelin Goncalves; Cortez Plaza, Cristian Andres [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile]; Billiald, Philippe; de Moura, Juliana Ferreira; Yoshida, Nobuko; Alvarenga, Larissa Magalhaes; DaRocha, Wanderson Duarte (Chile. Universidad Mayor, 2019-10-16)
      Trypanosoma cruzi is a flagellate protozoan pathogen that causes Chagas disease. Currently there is no preventive treatment and the efficiency of the two drugs available is limited to the acute phase. Therefore, there is ...
    • Advancements in the Synthesis of Building Block Materials: Experimental Evidence and Modeled Interpretations of the Effect of Na and K on Imogolite Synthesis 

      Arancibia-Miranda N., Escudey M., Ramírez R., Van Duin A.C.T., Kiwi M.; González Rafael I. [Centro de Genómica y Bioinformatica, Facultad de Ciencias, Universidad Mayor, Chile] (AMER CHEMICAL SOC, 2017)
      The effects of Na/K substitution during the synthesis of imogolite nanotubes (NTs) were studied using a combination of structural and surface analyses. These were complemented with molecular dynamics (MD) and DFT computational ...
    • Macroscopic nonclassical-state preparation via postselection 

      Montenegro V., Eremeev V.; Coto, Raúl [Universidad Mayor, Chile]; Orszag, Miguel [Universidad Mayor, Chile] (American Physical Society, 2017)
      Macroscopic quantum superposition states are fundamental to test the classical-quantum boundary and present suitable candidates for quantum technologies. Although the preparation of such states has already been realized, ...
    • Stimulated Raman adiabatic control of a nuclear spin in diamond 

      Jacques V., Hétet G., Maze J.R.; Coto, Raúl [Centro de Física y Nanotecnología, Facultad de Ciencias, Universidad Mayor, Chile] (American Physical Society, 2017)
      Coherent manipulation of nuclear spins is a highly desirable tool for both quantum metrology and quantum computation. However, most of the current techniques to control nuclear spins lack fast speed, impairing their ...
    • The power of a control qubit in weak measurements 

      Montenegro V., Eremeev V., Mundarain D., Orszag M.; Coto, Raúl [Universidad Mayor, Chile] (NATURE PUBLISHING GROUP, 2017)
      In the late 80 s, a curious effect suggested by Aharanov et al. was found to lead to an anomalous amplification based on quantum measurements of weakly coupled systems. In this paper, we investigate the quantum control of ...
    • Remnants of native forests support carnivore diversity in the vineyard landscapes of central Chile 

      Abades, Sebastián [Chile. Universidad Mayor. Facultad de Ciencias. Centro de Genómica, Ecología y Medio Ambiente]; García, Camila B.; Svensson, Gabriella L.; Bravo, Camila; Undurraga, María I.; Díaz-Forestier, Javiera; Godoy, Karina; Neaman, Alexander; Barbosa, Olga; Celis-Diez, Juan L. (Cambridge University Press, 2018-03)
      Carnivores play an important role in ecosystem functioning as apex predators. However, most carnivore species are threatened or have been extirpated in human-dominated landscapes. The Mediterranean region of central Chile ...
    • On the proportional abundance of species: Integrating population genetics and community ecology 

      Marquet P.A., Espinoza G., Ganz A., Rebolledo R.; Abades, Sebastián R. [Centro de Genómica, Ecología y Medio Ambiente, GEMA, Facultad de Ciencias, Universidad Mayor, Chile] (Nature Publishing Group, 2017)
      The frequency of genes in interconnected populations and of species in interconnected communities are affected by similar processes, such as birth, death and immigration. The equilibrium distribution of gene frequencies ...
    • Macroecological factors shape local-scale spatial patterns in agriculturalist settlements 

      Tao T., Teng S., Huang Z.Y.X., Reino L., Chen B.J.W., Zhang Y., Xu C., Svenning J.-C.; Abades, Sebastián [Centro de Genómica, Ecología y Medio Ambiente, GEMA, Universidad Mayor, Chile] (The Royal Society, 2017)
      Macro-scale patterns of human systems ranging from population distribution to linguistic diversity have attracted recent attention, giving rise to the suggestion that macroecological rules shape the assembly of human ...
    • Inducing Porosity on Hollow Nanoparticles by Hypervelocity Impacts 

      Valdivia J.A., Kiwi M., Bringa E.M., Rogan J.; Valencia, Felipe J. [Núcleo de Matemáticas, Física & Estadística, Facultad de Ciencias, Universidad Mayor, Chile]; González, Rafael I. [Centro de Genómica y Bioinformatica, Facultad de Ciencias, Universidad Mayor, Chile] (American Chemical Society, 2017)
      The large surface-to-volume ratio of hollow palladium nanoparticles (hNPs) offers room to improve their hydrogen storage capacity as well as their catalytic activity. However, a less explored possibility is to use, in ...
    • Hillock formation on nanocrystalline diamond 

      González R.I., Bringa E.M., Kiwi M.; Valencia Felipe J. [Núcleo de Matemáticas, Física y Estadística, Facultad de Ciencias, Universidad Mayor, Chile] (PERGAMON-ELSEVIER SCIENCE LTD, 2017)
      Hillock formation on nanocrystalline (nc) diamond under swift heavy ion irradiation is studied by means of classical molecular dynamics. The irradiation is simulated by means of a thermal spike model, the nc samples include ...
    • Composites of electrochemically reduced graphene oxide and polythiophene and their application in supercapacitors 

      Ibáñez-Marín F.; Camarada, M. B. [Centro de Nanotecnología Aplicada, Facultad de Ciencias, Universidad Mayor, Chile]; Morales-Verdejo, C. [Chile. Universidad Mayor. Facultad de Ciencias. Centro de Genómica y Bioinformática] (Electrochemical Science Group, 2017)
      Composite films consisting of polythiophene (PTh) and graphene oxide (GO) were synthetized by electrochemical polymerization. Consequently, the GO was reduced via cyclic voltammetry to form a reduced composite (PTh/rGO), ...
    • PAMAM Dendrimers as Support for the Synthesis of Gold Nanoparticles: Understanding the Effect of the Terminal Groups 

      Camarada, M.B. [Centro de Genómica y Bioinformatica, Facultad de Ciencias, Universidad Mayor, Chile] (American Chemical Society, 2017)
      The interaction between hydroxyl-, aldehyde-, and amino-terminated PAMAM GO dendrimers with gold nanoclusters Au (n = 2, 4, 6, and 8) was studied theoretically at the DFT level. Different coordination sites were explored, ...
    • Metagenome sequencing of the microbial community of a solar saltern crystallizer pond at C�huil Lagoon, Chile 

      Plominsky A.M., Delherbe N., Allen E.E., Blanchet M., Ikeda P., Santiba�ez F., Hanselmann K., Ulloa O., De la Iglesia R., von Dassow P., Astorga M., G�lvez M.J., Gonz�lez M.L., Henr�quez-Castillo C., Vaulot D., do Santos A.L., van den Engh G., Gimpel C., Bertoglio F., Delgado Y., Docmac F., Elizondo-Patrone C., Narv�ez S., Sorroche F.; Ugalde, Juan A. [Facultad de Ciencias, Universidad Mayor, Chile]; Rojas-Herrera, Marcelo [Facultad de Ciencias, Universidad Mayor, Chile]; Trefault, Nicole [Facultad de Ciencias, Universidad Mayor, Chile] (American Society for Microbiology, 2014)
      Cáhuil Lagoon in central Chile harbors distinct microbial communities in various solar salterns that are arranged as interconnected ponds with increasing salt concentrations. Here, we report the metagenome of the 3.0- to ...
    • Genome sequence of Vibrio VPAP30, isolated from an episode of massive mortality of reared larvae of scallop Argopecten purpuratus 

      Rojas R., Miranda C.D., Asenjo F.; Romero, Jaime [Centro de Genómica y Bioinformatica, Facultad de Ciencias, Universidad Mayor, Chile]; Valderrama, Katherinne [Microbial Pathogenesis & Vaccinol Res Grp, ‎Facultad de Ciencias, Universidad Mayor, Chile]; Segovia, Cristopher [Microbial Pathogenesis & Vaccinol Res Grp, ‎Facultad de Ciencias, Universidad Mayor, Chile]; Ugalde, Juan A. [Centro de Genómica y Bioinformatica, Facultad de Ciencias, Universidad Mayor, Chile]; Santander, Javier [Microbial Pathogenesis & Vaccinol Res Grp, ‎Facultad de Ciencias, Universidad Mayor, Chile] (American Society for Microbiology, 2015)
      We report here the 5.167-Mbp draft genome sequence of Vibrio VPAP30, isolated from an Argopecten purpuratus larval culture. Vibrio VPAP30 is the etiological agent of a vibriosis outbreak causing a complete collapse of a ...


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