Mostrando ítems 21-40 de 78

    • Implications of Selective Autophagy Dysfunction for ALS Pathology 

      Vicencio, Emiliano [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Beltrán, Sebastián [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Labrador, Luis [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Manque, Patricio [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Nassif, Melissa [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile]; Woehlbier, Ute [Univ Mayor, Fac Sci, Ctr Integrat Biol, Chile] (MDPI Multidisciplinary Digital Publishing Institute, 2020-02)
      Amyotrophic lateral sclerosis (ALS) is a lethal neurodegenerative disorder that progressively affects motor neurons in the brain and spinal cord. Due to the biological complexity of the disease, its etiology remains unknown. ...
    • Nitrate in 2020: Thirty Years from Transport to Signaling Networks 

      Vidal, Elena A. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile]; Alvarez, Jose M. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile]; Araus, Viviana; Riveras, Eleodoro; Brooks, Matthew D.; Krouk, Gabriel; Ruffel, Sandrine; Lejay, Laurence; Crawford, Nigel M.; Coruzzi, Gloria M.; Gutierrez, Rodrigo A. (American Society of Plant Biologists, 2020-07)
      Nitrogen (N) is an essential macronutrient for plants and a major limiting factor for plant growth and crop production. Nitrate is the main source of N available to plants in agricultural soils and in many natural environments. ...
    • Outline of Fungi and fungus-like taxa 

      Wijayawardene, NN; Hyde, KD; Al-Ani, LKT; Tedersoo, L.; Haelewaters, D; Rajeshkumar, KC; Zhao, RL; Aptroot, A; Leontyev, DV; Saxena, RK; Tokarev, YS; Dai, DQ; Letcher, PM; Stephenson, SL; Ertz, D; Lumbsch, HT; Kukwa, M; Issi, IV; Phillips, AJL; Selbmann, L; Pfliegler, WP; Horvath, E; Bensch, K; Kirk, PM; Kolarikova, K; Raja, HA; Radek, R; Papp, V; Dima, B; Ma, J; Malosso, E; Takamatsu, S; Rambold, G; Gannibal, PB; Triebel, D; Gautam, AK; Avasthi, S; Suetrong, S; Timdal, E; Fryar, SC; Delgado, G; Reblova, M; Doilom, M; Dolatabadi, S; Pawlowska, JZ; Humber, RA; Kodsueb, R; Sanchez-Castro, I; Goto, BT; Silva, DKA; de Souza, FA; Oehl, FR; da Silva, GA; Silva, IR; Blaszkowski, J; Jobim, K; Maia, LC; Barbosa, FR; Fiuza, PO; Divakar, PK; Shenoy, BD; Castaneda-Ruiz, RF; Somrithipol, S; Lateef, AA; Karunarathna, SC; Tibpromma, S; Mortimer, PE; Wanasinghe, DN; Phookamsak, R; Xu, J; Wang, Y; Tian, F; Alvarado, P; Li, DW; Kusan, I; Matocec, N; Mesic, A; Tkalcec, Z; Maharachchikumbura, SSN; Papizadeh, M; Heredia, G; Wartchow, F; Bakhshi, M; Boehm, E; Youssef, N; Hustad, VP; Lawrey, JD; Santiago, ALCMA; Bezerra, JDP; Souza-Motta, CM; Firmino, AL; Tian, Q; Houbraken, J; Hongsanan, S; Tanaka, K; Dissanayake, AJ; Monteiro, JS; Grossart, HP; Suija, A; Weerakoon, G; Etayo, J; Tsurykau, A; Vazquez, V; Mungai, P ; Damm, U; Li, QR; Zhang, H; Boonmee, S; Lu, YZ; Becerra, AG; Kendrick, B; Brearley, FQ; Motiejunaite, J; Sharma, B; Khare, R; Gaikwad, S; Wijesundara, DSA; Tang, LZ; He, MQ; Flakus, A; Rodriguez-Flakus, P; Zhurbenko, MP; McKenzie, EHC; Stadler, M; Bhat, DJ; Liu, JK; Raza, M; Jeewon, R; Nassonova, ES; Prieto, M; Jayalal, RGU; Erdogdu, M; Yurkov, A; Schnittler, M; Shchepin, ON; Novozhilov, YK; Silva, AGS; Gentekaki, E; Liu, P; Cavender, JC; Kang, Y; Mohammad, S; Zhang, LF; Xu, RF; Li, YM; Dayarathne, MC; Ekanayaka, AH; Wen, TC; Deng, CY; Pereira, OL; Navathe, S; Hawksworth, DL; Fan, XL; Dissanayake, LS; Kuhnert, E; Thines, M; Madrid, H. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile] (Guizhou Key Laboratory of Agricultural Biotechnology, 2020)
      This article provides an outline of the classification of the kingdom Fungi (including fossil fungi. i.e. dispersed spores, mycelia, sporophores, mycorrhizas). We treat 19 phyla of fungi. These are Aphelidiomycota, Ascomycota, ...
    • Gene Regulatory Networks of Penicillium echinulatum 2HH and Penicillium oxalicum 114-2 Inferred by a Computational Biology Approach 

      Lenz, Alexandre Rafael; Galán-Vásquez, Edgardo; Balbinot, Eduardo; de Abreu, Fernanda Pessi; Souza de Oliveira, Nikael; da Rosa, Leticia Osorio; de Avila e Silva, Scheila; Camassola, Marli; Dillon, Aldo Jose Pinheiro; Pérez-Rueda, Ernesto [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile] (Frontiers Media S.A., 2020-10)
      Penicillium echinulatum 2HH and Penicillium oxalicum 114-2 are well-known cellulase fungal producers. However, few studies addressing global mechanisms for gene regulation of these two important organisms are available so ...
    • Dormant but Active: Chilling Accumulation Modulates the Epigenome and Transcriptome ofPrunus aviumDuring Bud Dormancy 

      Rothkegel, Karin; Sandoval, Paula; Soto, Esteban; Ulloa, Lissette; Riveros, Anibal; Lillo-Carmona, Victoria; Caceres-Molina, Javier; Almeida, Andrea Miyasaka [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile]; Meneses, Claudio (Frontiers Media S.A., 2020-07)
      Temperate deciduous fruit tree species like sweet cherry (Prunus avium) require long periods of low temperatures to trigger dormancy release and flowering. In addition to sequence-based genetic diversity, epigenetic variation ...
    • Deciphering the functional diversity of DNA-binding transcription factors in Bacteria and Archaea organisms 

      Flores-Bautista, Emanuel; Hernández-Guerrero, Rafael; Huerta-Saquero, Alejandro; Tenorio-Salgado, Silvia; Rivera-Gómez, Nancy; Romero, Alba; Antonio Ibarra, José; Pérez-Rueda, Ernesto [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile] (Public Library of Science, 2020-08)
      DNA-binding Transcription Factors (TFs) play a central role in regulation of gene expression in prokaryotic organisms, and similarities at the sequence level have been reported. These proteins are predicted with different ...
    • Bacterially produced metabolites protect C. elegans neurons from degeneration 

      Urrutia, Arles; García-Angulo, Víctor A. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile]; Fuentes, Andres [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile]; Caneo, Mauricio; Legue, Marcela [Univ Mayor, Fac Ciencias, Ctr Genom Integrat, Chile]; Urquiza, Sebastian [Univ Mayor, Fac Ciencias, Ctr Genom Integrat, Chile]; Delgado, Scarlett E. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile]; Ugalde, Juan [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile]; Burdisso, Paula; Calixto, Andrea [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile] (Public Library of Science, 2020-03)
      Caenorhabditis elegans and its cognate bacterial diet comprise a reliable, widespread model to study diet and microbiota effects on host physiology. Nonetheless, how diet influences the rate at which neurons die remains ...
    • The Microbial Composition in Circumneutral Thermal Springs from Chignahuapan, Puebla, Mexico Reveals the Presence of Particular Sulfur-Oxidizing Bacterial and Viral Communities 

      Castelan-Sánchez, Hugo Gildardo; Meza-Rodríguez, Pablo M.; Carrillo, Erika; Ríos-Vázquez, David I.; Linan-Torres, Arturo; Batista-Garcia, Ramón Alberto; Pérez-Rueda, Ernesto [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile]; Rojas-Ruíz, Norma Elena; Dávila-Ramos, Sonia (MDPI AG, 2020-11)
      Terrestrial thermal springs are widely distributed globally, and these springs harbor a broad diversity of organisms of biotechnological interest. In Mexico, few studies exploring this kind of environment have been described. ...
    • Transcriptomic analysis at organ and time scale reveals gene regulatory networks controlling the sulfate starvation response ofSolanum lycopersicum 

      Canales, Javier; Uribe, Felipe; Henríquez-Valencia, Carlos; Lovazzano, Carlos; Medina, Joaquín; Vidal, Elena A. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile] (Chile. Universidad Mayor, 2020)
      Background Sulfur is a major component of biological molecules and thus an essential element for plants. Deficiency of sulfate, the main source of sulfur in soils, negatively influences plant growth and crop yield. The ...
    • Understanding gold toxicity in aerobically-grown Escherichia coli 

      Muñoz-Villagrán, C.; Contreras, F.; Cornejo, F.; Figueroa, M.; Valenzuela-Bezanilla, D.; Luraschi, R.; Reinoso, C.; Rivas-Pardo, J. [Univ Mayor, Lab Biol Estruct, Ctr Genom & Bioinformat, Chile]; Vásquez, C.; Castro, M.; Arenas, F. (Chile. Universidad Mayor, 2020)
      Background There is an emerging field to put into practice new strategies for developing molecules with antimicrobial properties. In this line, several metals and metalloids are currently being used for these purposes, ...
    • A dynamic portal for a community-driven, continuously updated classification of Fungi and fungus-like organisms: outlineoffungi.org 

      Madrid, H. [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile]; Wijayawardene, N. N.; Hyde, K. D.; Dai, D. Q.; Tang, L. Z.; Aptroot, A.; Castaneda-Ruiz, R. F.; Druzhinina, I. S.; Cai, F.; Ekanayaka, A. H.; Erdogdu, M.; Fiuza, P. O.; Gentekaki, E.; Goto, B. T.; Haelewaters, D.; Hongsanan, S.; Jeewon, R.; Kirk, P. M.; Jayalal, R. G. U.; Karunarathna, S. C.; Wanasinghe, D. N.; Lumbsch, H. T.; Maharachchikumbura, S. S. N.; Monteiro, J. S.; Shivaprakash, N.; Pfliegler, W. P.; Phillips, A. J. L.; Saxena, R. K.; Stadler, M.; Tian, Q.; Tokarev, Y. S.; Tsurykau, A.; Ertz, D.; Lee, H. B.; Etayo, J.; Vizzini, A.; Jones, E. B. G.; Lin, C. G.; Li, W. J.; Dai, Y. C.; Fan, X. L.; McKenzie, E. H. C.; Shivas, R. G.; Hustad, V.; Leontyev, D., V.; de Hoog, G. S.; Niskanen, T.; Boekhout, T.; Gaya, E.; Thines, M. (Chile. Universidad Mayor, 2020)
      The website http://outlineoffungi.org, is launched to provide a continuous up-to-date classification of the kingdom Fungi (including fossil fungi) and fungus-like taxa. This is based on recent publications and on the outline ...
    • Chloropicophyceae, a new class of picophytoplanktonic prasinophytes 

      Lopes dos Santos, Adriana [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile]; Pollina, Thibaut; Gourvil, Priscillia; Corre, Erwan; Marie, Dominique; Luis Garrido, José; Rodríguez, Francisco; Noel, Mary-Helene; Vaulot, Daniel; Eikrem, Wenche (Chile. Universidad Mayor, 2016)
      Prasinophytes are a paraphyletic group of nine lineages of green microalgae that are currently classified either at the class or order level or as clades without formal taxonomic description. Prasinophyte clade VII comprises ...
    • High-Quality Draft Genome Sequence of Bacillus amyloliquefaciens Strain 629, an Endophyte from Theobroma cacao 

      SantAnna, Brena M. M.; Marbach, Phellippe P. A.; De Souza, Jorge T.; Rojas-Herrera, Marcelo [Univ Mayor, Ctr Genom & Bioinformat, Chile]; Roque, Milton R. A.; Queiroz, Artur T. L. (Chile. Universidad Mayor, 2015)
      Bacillus amyloliquefaciens strain 629 is an endophyte isolated from Theobroma cacao L. Here, we report the draft genome sequence (3.9 Mb) of B. amyloliquefaciens strain 629 containing 16 contigs (3,903,367 bp), 3,912 coding ...
    • Thinning alters the expression of the PpeSUT1 and PpeSUT4 sugar transporter genes and the accumulation of translocated sugars in the fruits of an early season peach variety 

      Núñez, Carlos [Univ Mayor, Ctr Genom & Bioinformat, Fac Ciencias, Chile]; Dupre, German; Mujica, Karen; Melet, Lorena; Meisel, Lee; Miyasaka Almeida, Andrea [Univ Mayor, Ctr Genom & Bioinformat, Fac Ciencias, Chile] (Chile. Universidad Mayor, 2019)
      Thinning is an agronomic practice that consists in the removal of a certain number of fruits, thereby altering the source-sink equilibrium in the tree and favoring carbon allocation to the remaining fruits. If thinning is ...
    • Partitioning beta-diversity reveals that invasions and extinctions promote the biotic homogenization of Chilean freshwater fish fauna 

      Castro, Sergio A.; Rojas, Pablo; Vila, Irma; Habit, Evelyn; Pizarro-Konczak, Jaime; Jaksic, Fabian M.; Abades, Sebastián [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Chile] (Chile. Universidad Mayor, 2020)
      Aim Exotic species' introductions together with extinction of native species represent the main mechanisms driving biotic homogenization of freshwater fish assemblages around the world. While generally ichtyofaunistic ...
    • AciDB 1.0: a database of acidophilic organisms, their genomic information and associated metadata 

      Neira, Gonzalo; Cortez, Diego; Jil, Joaquín; Holmes, David S. [Chile. Universidad Mayor. Facultad de Ciencias. Centro de Investigación de Genómica y Bioinformática] (OXFORD UNIV PRESS, 2020-10-01)
      Motivation: There are about 600 available genome sequences of acidophilic organisms (grow at a pH<5) from the three domains of the Tree of Life. Information about acidophiles is scattered over many heterogeneous sites ...
    • Genome-based classification of Acidihalobacter prosperus F5 (=DSM 105917=JCM 32255) as Acidihalobacter yilgarnensis sp. nov 

      Khaleque, Himel Nahreen; González, Carolina [Chile. Universidad Mayor. Facultad de Ciencias. Centro de Investigación de Genómica y Bioinformática]; Johnson, D Barrie; Kaksonen, Anna H.; Holmes, David S. [Chile. Universidad Mayor. Facultad de Ciencias. Centro de Investigación de Genómica y Bioinformática]; Watkin, Elizabeth L. J. (MICROBIOLOGY SOCIETY, 2020-12)
      The genus Acidihalobacter has three validated species, Acidihalobacter ferrooxydans, Acidihalobacter prosperus and Acidihalobacter aeolinanus, all of which were isolated from Vulcano island, Italy. They are obligately ...
    • DEF8 and Autophagy-Associated Genes are Altered in Mild Cognitive Impairment, Probable Alzheimer’s Disease Patients and a Transgenic Model of the Disease 

      Leyton, Esteban [Chile. Universidad Mayor. Centro de Biología Integrativa]; Matus, Diego [Chile. Universidad Mayor. Centro de Biología Integrativa]; Espinoza, Sandra [Chile. Universidad Mayor. Centro de Biología Integrativa]; Benítez, José Matías [Chile. Universidad Mayor. Centro de Biología Integrativa]; Cortés, Bastián [Chile. Universidad Mayor. Centro de Biología Integrativa]; Gómez, Wileidy [Chile. Universidad Mayor. Centro de Biología Integrativa]; Arévalo, Nohela B. [Chile. Universidad Mayor. Centro de Biología Integrativa]; Murgas, Paola [Chile. Universidad Mayor. Centro de Biología Integrativa]; Manque Ramírez, Patricio [Chile. Universidad Mayor. Centro de Genómica y Bioinformática]; Woehlbier, Ute [Chile. Universidad Mayor. Centro de Biología Integrativa]; Durán-Aniotz, Claudia; Hetz, Claudio; Behrens, María Isabel; San Martín, Carol D. [Chile. Universidad Mayor. Centro de Biología Integrativa]; Nassif, Melissa [Chile. Universidad Mayor. Centro de Biología Integrativa] (IOS Press, 2021-02-19)
      Background:Disturbances in the autophagy/endolysosomal systems are proposed as early signatures of Alzheimer’s disease (AD). However, few studies are available concerning autophagy gene expression in AD patients. Objective:To ...
    • Rule-Based Models and Applications in Biology 

      Bustos, Álvaro; Fuenzalida, Ignacio; Santibáñez, Rodrigo; Pérez-Acle, Tomás; Martin, Alberto J M [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile] (Humana Press, 2018-11-13)
      Complex systems are governed by dynamic processes whose underlying causal rules are difficult to unravel. However, chemical reactions, molecular interactions, and many other complex systems can be usually represented as ...
    • The protein architecture in Bacteria and Archaea identifies a set of promiscuous and ancient domains 

      Hernández-Guerrero, Rafael; Galán-Vásquez, Edgardo; Pérez-Rueda, Ernesto [Centro de Genómica y Bioinformática, Facultad de Ciencias, Universidad Mayor, Chile] (Public Library of Science, 2019-12-19)
      In this work, we describe a systematic comparative genomic analysis of promiscuous domains in genomes of Bacteria and Archaea. A quantitative measure of domain promiscuity, the weighted domain architecture score (WDAS), ...


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