Mostrando ítems 3581-3600 de 7967

    • The relationship between coping styles and responses to handling in captive guanacos (Lama guanicoe) 

      Zapata, Beatriz [Univ Mayor, Fac Ciencias, Escuela Biotecnol]; Riveros F, JoséLuis; Correa, Lina Maria; Goddard, Pete; Bonacic, Cristián (ELSEVIER, 2019)
      The objective of the present study was to evaluate the coping style response to handling of guanacos (Lama guanicoe) in captivity. This study contributes to a better understanding of the handling effect in captivity of the ...
    • Early postnatal environmental enrichment restores neurochemical and functional plasticities of the cerebral cortex and improves learning performance in hidden-prenatally-malnourished young-adult rats 

      Burgos, Héctor [Univ Mayor, Sch Psychol, Santiago, Chile]; Hernández, Alejandro; Constandil, Luis; Rios, Miguel; Flores, Osvaldo; Puentes, Gustavo; Hernández, Karina; Morgan, Carlos; Valladares, Luis; Castillo, Amparo; Cofré, Christian; Milla, Luis A.; Saez-Briones, Patricio; Barra, Rafael (ELSEVIER SCIENCE BV, 2019)
      Moderate reduction of dietary protein (from 25% to 8% casein) in pregnant rats, calorically compensated by carbohydrates, gives rise to 'hidden prenatal malnutrition' (HPM) in the offspring since it does not alter body and ...
    • Reduction of high-fat diet-induced liver proinflammatory state by eicosapentaenoic acid plus hydroxytyrosol supplementation: involvement of resolvins RvE1/2 and RvD1/2 

      González-Manan, D. [Univ Mayor, Fac Ciencias, Nucleo Quim & Bioquim, Santiago, Chile]; Echeverria, F.; Valenzuela, R.; Espinosa, A.; Bustamante, A.; Alvarez, D.; Ortiz, M.; Soto-Alarcón, S. A.; Videla, L. A. (ELSEVIER SCIENCE INC, 2019)
      High-fat diet (HFD)-fed mice show obesity with development of liver steatosis and a proinflammatory state without establishing an inflammatory reaction. The aim of this work was to assess the hypothesis that eicosapentaenoic ...
    • Relaciones intersubjetivas en el campo de la interculturalidad: saberes culturales mapuches 

      Beltrán Véliz, Juan [Univ Mayor, Programa Magister, Santiago, Chile]; Osses Bustingorry, Sonia; del Valle Rojas, Carlos; Mansilla Sepúlveda, Juan (UNIV CONCEPCION, BIBLIOTECA CENTRAL, 2019)
      El presente artículo se propone refl exionar en torno a las relaciones intersubjetivas en el campo de la interculturalidad. Desde esta perspectiva, es posible señalar que el diálogo juega un rol importante, pues es un ...
    • Measuring Relationships Between Proactive Reporting State-level Prescription Drug Monitoring Programs and County-level Fatal Prescription Opioid Overdoses 

      Castillo-Carniglia, Alvaro [Univ Mayor, Fac Humanidades, Soc & Hlth Res Ctr]; Cerda, Magdalena; Ponicki, William R.; Smith, Nathan; Rivera-Aguirre, Ariadne; Davis, Corey S.; Marshall, Brandon D. L.; Fink, David S.; Henry, Stephen G.; Wintemute, Garen J.; Gaidus, Andrew; Gruenewald, Paul J.; Martins, Silvia S. (LIPPINCOTT WILLIAMS & WILKINS, 2020)
      Background: Prescription drug monitoring programs (PDMPs) that collect and distribute information on dispensed controlled substances have been adopted by nearly all US states. We know little about program characteristics ...
    • All the music. Sound and cultural diversity of Peru 

      Spencer Espinosa, Christian [Univ Mayor, Fac Artes, CIAH, Santiago, Chile] (PONTIFICIA UNIV CATOLICA CHILE, 2019)
      Sin resumen
    • Margot Loyola, the infinite scene of folklore 

      Ramos Rodillo, Ignacio [Univ Mayor] (PONTIFICIA UNIV CATOLICA CHILE, FAC LETRAS, 2019)
      Sin resumen
    • Paradise and Perdition: Jesuit Visions of Santiago, Chile, before and after the Earthquake of 1647 

      Burdick, Catherine [Univ Mayor, Fac Artes, Ctr Invest Artes & Humanidades, Hist] (DUKE UNIV PRESS, 2019)
      This study inserts Santiago, Chile, into contemporary discussions of colonial Latin America by reading two Jesuit documents-a map and a letter-created prior to and following the devastating earthquake of 1647, respectively. ...
    • The Gifted Passage: Young Men in Classic Maya Art and Text 

      Burdick, Catherine [Univ Mayor, Fac Artes, Art Hist, Santiago, Chile] (UNIV CHICAGO PRESS, 2019)
      Sin resumen
    • Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation 

      Rojas-Rivera, Diego [Univ Mayor, Fac Sci, Ctr Integrat Biol]; Dondelinger, Yves; Delanghe, Tom; Priem, Dario; Wynosky-Dolfi, Meghan A.; Sorobetea, Daniel; Giansanti, Piero; Roelandt, Ria; Gropengiesser, Julia; Ruckdeschel, Klaus; Savvides, Savvas N.; Heck, Albert J. R.; Vandenabeele, Peter; Brodsky, Igor E.; Bertrand, Mathieu J. M. (NATURE PUBLISHING GROUP, 2019)
      RIPK1 regulates cell death and inflammation through kinase-dependent and -independent mechanisms. As a scaffold, RIPK1 inhibits caspase-8-dependent apoptosis and RIPK3/MLKL-dependent necroptosis. As a kinase, RIPK1 ...
    • The Protein Tyrosine Phosphatase Receptor Delta Regulates Developmental Neurogenesis 

      Cancino, Gonzalo I. [Univ Mayor, Fac Ciencias, Ctr Integrat Biol]; Aranda-Pino, Begoña [Univ Mayor, Fac Ciencias, Ctr Integrat Biol]; Cornejo, Francisca [Univ Mayor, Fac Ciencias, Ctr Integrat Biol]; Tomita, Hideaki; Woodard, Cameron L.; Rioseco, Constanza C.; Neel, Benjamin G.; Alvarez, Alejandra R.; Kaplan, David R.; Miller, Freda D. (CELL PRESS, 2020)
      PTPRD is a receptor protein tyrosine phosphatase that is genetically associated with neurodevelopmental disorders. Here, we asked whether Ptprd mutations cause aberrant neural development by perturbing neurogenesis in the ...
    • The Oculome Panel Test: Next-Generation Sequencing to Diagnose a Diverse Range of Genetic Developmental Eye Disorders 

      Valdivia, Leonardo E. [Univ Mayor, Fac Ciencias, Ctr Integrat Biol, Santiago, Chile]; Patel, Aara; Hayward, Jane D.; Tailor, Vijay; Nyanhete, Rodney; Ahlfors, Helena; Gabriel, Camila; Jannini, Tommaso B.; Abbou-Rayyah, Yassir; Henderson, Robert; Nischal, Ken K.; Islam, Lily; Bitner-Glindzicz, Maria; Hurst, Jane; Zanolli, Mario; Moosajee, Mariya; Brookes, John; Papadopoulos, Maria; Khaw, Peng T.; Cullup, Thomas; Jenkins, Lucy; Dahlmann-Noor, Annegret; Sowden, Jane C. (ELSEVIER SCIENCE INC, 2019)
      Purpose: To develop a comprehensive next-generation sequencing panel assay that screens genes known to cause developmental eye disorders and inherited eye disease and to evaluate its diagnostic yield in a pediatric cohort ...
    • Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes 

      Riquelme, Erick [Univ Mayor, Fac Sci, Ctr Integrat Biol, Santiago, Chile]; Zhang, Yu; Zhang, Liangliang; Montiel, Maria; Zoltan, Michelle; Dong, Wenli; Quesada, Pompeyo; Sahin, Ismet; Chandra, Vidhi; San Lucas, Anthony; Scheet, Paul; Xu, Hanwen; Hanash, Samir M.; Feng, Lei; Burks, Jared K.; Do, Kim-Anh; Peterson, Christine B.; Nejman, Deborah; Tzeng, Ching-Wei D.; Kim, Michael P.; Sears, Cynthia L.; Ajami, Nadim; Petrosino, Joseph; Wood, Laura D.; Maitra, Anirban; Straussman, Ravid; Katz, Matthew; White, James Robert; Jenq, Robert; Wargo, Jennifer; McAllister, Florencia (CELL PRESS, 2019)
      Most patients diagnosed with resected pancreatic adenocarcinoma (PDAC) survive less than 5 years, but a minor subset survives longer. Here, we dissect the role of the tumor microbiota and the immune system in influencing ...
    • Abrogation of Stem Loop Binding Protein (Slbp) function leads to a failure of cells to transition from proliferation to differentiation, retinal coloboma and midline axon guidance deficits 

      Valdivia, Leonardo E. [Univ Mayor, Fac Ciencias, Ctr Integrat Biol, Santiago, Chile]; Turner, Katherine J.; Hoyle, Jacqueline; Cerveny, Kara L.; Hart, Wendy; Mangoli, Maryam; Geisler, Robert; Rees, Michele; Houart, Corinne; Poole, Richard J.; Wilson, Stephen W.; Gestri, Gaia (PUBLIC LIBRARY SCIENCE, 2019)
      Through forward genetic screening for mutations affecting visual system development, we identified prominent coloboma and cell-autonomous retinal neuron differentiation, lamination and retinal axon projection defects in ...
    • Down syndrome and Alzheimer's disease: common molecular traits beyond the amyloid precursor protein 

      Nassif, Melissa [Univ Mayor, Fac Sci, Ctr Integrat Biol, Lab Neuroprotect & Autophagy, Santiago, Chile]; Gómez, Wileidy [Univ Mayor, Fac Sci, Ctr Integrat Biol, Lab Neuroprotect & Autophagy, Santiago, Chile]; Morales, Rodrigo; Maracaja-Coutinho, Vinicius; Parra, Valentina (IMPACT JOURNALS LLC, 2020)
      Alzheimer's disease (AD) is the most prevalent type of dementia. Down syndrome (DS) is the leading genetic risk factor for Early-Onset AD, prematurely presenting the classic pathological features of the brain with AD. ...
    • Network approach identifies Pacer as an autophagy protein involved in ALS pathogenesis 

      Woehlbier, U. [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Camino Piramide]; Manque, P. A.[Univ Mayor, Ctr Genom & Bioinformat, Fac Sci]; Hernández, M. F. [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Camino Piramide]; Bergmann, C. A. [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Camino Piramide]; Cortez, C. [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci]; Cortés, B. I. [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci]; Labrador, L. [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci]; Arcos, J. [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci]; Vicencio, E. [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci]; Nassif, M. [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci] (BMC, 2019)
      BackgroundAmyotrophic lateral sclerosis (ALS) is a multifactorial fatal motoneuron disease without a cure. Ten percent of ALS cases can be pointed to a clear genetic cause, while the remaining 90% is classified as sporadic. ...
    • MTOR-independent autophagy induced by interrupted endoplasmic reticulum-mitochondrial Ca2+ communication: a dead end in cancer cells 

      Silva-Pavez, Eduardo [Univ Mayor, Ctr Integrat Biol, Fac Sci, Santiago, Chile]; Ahumada-Castro, Ulises [Univ Mayor, Ctr Integrat Biol, Fac Sci, Santiago, Chile]; Lovy, Alenka; Pardo, Evelyn; Molgo, Jordi; Cardenas, César (TAYLOR & FRANCIS INC, 2019)
      The interruption of endoplasmic reticulum (ER)-mitochondrial Ca2+ communication induces a bioenergetic crisis characterized by an increase of MTOR-independent AMPK-dependent macroautophagic/autophagic flux, which is not ...
    • ABL1 kinase inhibitors for the treatment of Niemann-Pick disease type A 

      Cortez, Cristián [Univ Mayor, Santiago, Chile]; Zanlungo, Silvana; Marin, Tamara; De la Fuente, Catalina; Acuna, Mariana; Campos, Fabian; Castro, Juan; Leal, Nancy; Marugan, Juan; Dulcey, Andres; Gorshkov, Kirill; Zheng, Wei; Carmo-Fonseca, Maria; Alvarez, Alejandra R. (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2020)
      Sin resumen
    • Cómo se desarrolla el proceso enseñanza-aprendizaje de los estudiantes de primero y segundo año básico que participan del Programa de Integración Escolar, a la luz de la implementación del Decreto N°83/2015 

      Arias Arévalo, María Teresa; Carreño Becerra, Sandra (Chile. Universidad Mayor, 2018)
      En un enfoque inclusivo que atiende las necesidades de cada estudiante, nace la condición de dar respuesta a las demandas para brindar a todas y todos los estudiantes una educación escolar adecuada y de calidad en un ...
    • Diseño de un protocolo de Evaluación/Detección de tartamudez infantil (PEDTI) 

      Jofré Alquinta, Barbara; Miranda Muñoz, Raisa (Chile. Universidad Mayor, 2017)
      La tartamudez es un trastorno de la comunicación que afecta la fluidez del habla caracterizada por repeticiones, interrupciones, prolongaciones de sonidos, movimientos de cara y cuerpo acompañados de tensión y que puede ...


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