Repositorio UMAYOR: Envíos recientes
Mostrando ítems 3601-3620 de 8200
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Ketogenic diet ameliorates dysferlinopathy phenotype in Dysf-/-mice by promoting mitochondrial function
(PERGAMON-ELSEVIER SCIENCE LTD, 2019)Sin resumen -
Factors associated with cognitive impairment in older adults in Chile
(SOC MEDICA SANTIAGO, 2019)Background: The risk factors for the development of cognitive impairment are not well known. Aim: To identify socio-demographic, lifestyle and health-related factors associated with cognitive impairment in older Chilean ... -
Association of the TCF7L2 (RS7903146) genotype with adiposity and metabolic markers in the Chilean adult population
(SOC MEDICA SANTIAGO, 2019)Background: Type 2 diabetes etiology has a strong genetic component. More than 20 genetic variants have been associated with diabetes and other metabolic markers. However, the polymorphism rs7903146 of the TCF7L2 gene has ... -
Coagulation Factor Xa Promotes Solid Tumor Growth, Experimental Metastasis and Endothelial Cell Activation
(MDPI, 2019)Hypercoagulable state is linked to cancer progression; however, the precise role of the coagulation cascade is poorly described. Herein, we examined the contribution of a hypercoagulative state through the administration ... -
Nanopore Sequencing Significantly Improves Genome Assembly of the Protozoan Parasite Trypanosoma cruzi
(OXFORD UNIV PRESS, 2019)Chagas disease was described by Carlos Chagas, who first identified the parasite Trypanosoma cruzi from a 2-year-old girl called Berenice. Many T. cruzi sequencing projects based on short reads have demonstrated that genome ... -
Adherence to physical activity recommendations across age categories: Findings from the 2009-2010 Chilean National Health Survey
(SOC CHILENA NUTRICION, BROMATOLOGIA & TOXICOLOGIA, 2019)Although physical activity (PA) is a protective factor against non-communicable diseases, there is an important proportion of the population who do not meet PA guidelines. Our aim was to investigate how adherence to PA ... -
c-Jun N-terminal kinase (JNK)-dependent internalization and Rab5-dependent endocytic sorting mediate long-distance retrograde neuronal death induced by axonal BDNF-p75 signaling
(NATURE PUBLISHING GROUP, 2019)During the development of the sympathetic nervous system, signals from tropomyosin-related kinase receptors (Trks) and p75 neurotrophin receptors (p75) compete to regulate survival and connectivity. During this process, ... -
Cognitive impairment in heart failure is associated with altered Wnt signaling in the hippocampus
(IMPACT JOURNALS LLC, 2019)Age represents the highest risk factor for death due to cardiovascular disease. Heart failure (HF) is the most common cardiovascular disease in elder population and it is associated with cognitive impairment (CI), diminishing ... -
Oral contraceptive use and depression among adolescents
(ELSEVIER SCIENCE INC, 2019)Purpose: Depression is a prevalent health problem affecting U.S. women. Oral contraceptive pills (OCPs) are commonly used for pregnancy prevention, and evidence is mixed regarding any increased risk for incident depression ... -
Rostral ventrolateral medullary catecholaminergic neurones mediate irregular breathing pattern in volume overload heart failure rats
(WILEY, 2019)Key points A strong association between disordered breathing patterns, elevated sympathetic activity, and enhanced central chemoreflex drive has been shown in experimental and human heart failure (HF). The aim of this study ... -
Prescription drug monitoring programs operational characteristics and fatal heroin poisoning
(ELSEVIER, 2019)Background: Prescription drug monitoring programs (POMP), by reducing access to prescribed opioids (POs), may contribute to a policy environment in which some people with opioid dependence are at increased risk for ... -
Neurocognitive Disorders in Heart Failure: Novel Pathophysiological Mechanisms Underpinning Memory Loss and Learning Impairment
(SPRINGER, 2019)Heart failure (HF) is a major public health issue affecting more than 26 million people worldwide. HF is the most common cardiovascular disease in elder population; and it is associated with neurocognitive function decline, ... -
The Term Muscle and its Internal Coherence: A Suggestion to Terminologia Histologica
(SOC CHILENA ANATOMIA, 2019)Terminologia Histologica (TH) was prepared following the indications of the International Committee on Anatomical Terminology (FIPAT), however, it is not exempt from errors and inconsistencies. the above information is ... -
Subtypes of minimal residual disease, association with Gleason score, risk and time to biochemical failure in pT2 prostate cancer treated with radical prostatectomy
(CANCER INTELLIGENCE LTD, 2019)Introduction: The Gleason score is a strong prognostic factor for treatment failure in pathologically organ-confined prostate cancer (pT2) treated by radical prostatectomy (RP). However, within each Gleason score, there ... -
Association of rs3751812 polymorphism of the FTO gene with adiposity and metabolic markers in Chilean population. Results of the GENADIO study
(ARAN EDICIONES, S L, 2019)Background: genetic variants of the FTO gene confer the highest risk of obesity identified so far. Associations between the FTO gene and alterations in metabolic markers have been reported in different populations but not ... -
Effect of FOLFOX on minimal residual disease in Stage III colon cancer and risk of relapse
(CANCER INTELLIGENCE LTD, 2019)Introduction: 25% of Stage III colon cancer patients relapse within 5 years due to minimal residual disease (MRD) not eliminated by surgery and chemotherapy. We hypothesise that sub-types of MRD, defined by circulating ... -
Simulating the Suicide Prevention Effects of Firearms Restrictions Based on Psychiatric Hospitalization and Treatment Records: Social Benefits and Unintended Adverse Consequences
(AMER PUBLIC HEALTH ASSOC INC, 2019)Objectives. To estimate We number or lives saved From Firearms suicide with expansions of gun restrictions based on mental health compared with the number who would be unnecessarily restricted. Methods. Agent-based models ... -
Determining Significant Morphological and Hemodynamic Parameters to Assess the Rupture Risk of Cerebral Aneurysms
(SPRINGER HEIDELBERG, 2019)Hemodynamics and morphology are recognized as major factors in the rupture risk of cerebral aneurysms, and exploration of their relationship is necessary to establish a method that can be employed by clinicians to assess ... -
Osteogenerative behavior of a new xenograft in a maxillary sinus lift: computed tomographic and histological findings
(E-CENTURY PUBLISHING CORP, 2019)The installation of implants in the maxillary posterior area is currently a challenge in implant-supported rehabilitation, which is why most of the times the maxillary zone must be reconstructed with different types of ...