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Mostrando ítems 938-957 de 1852
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Insulin-like growth factor 2 (IGF2) protects against Huntington's disease through the extracellular disposal of protein aggregates
(SPRINGER, 2020-11)Impaired neuronal proteostasis is a salient feature of many neurodegenerative diseases, highlighting alterations in the function of the endoplasmic reticulum (ER). We previously reported that targeting the transcription ... -
Insumos utilizados en la preparación de alimentos en producción porcina y su potencial de contaminación por dioxinas en la carne
(CIENCIAS, 2011)En el presente estudio se evaluó la contribución de los diversos insumos utilizados en la alimentación de los cerdos, como fuente de contaminación de dioxinas, furanos y bifenilos policlorados similares a dioxinas (DL-PCBs) ... -
Integrated genomic epidemiology and phenotypic profiling of Clostridium difficile across intra-hospital and community populations in Colombia
(NATURE PUBLISHING GROUP, 2019)Clostridium difficile, the causal agent of antibiotic-associated diarrhea, has a complex epidemiology poorly studied in Latin America. We performed a robust genomic and phenotypic profiling of 53 C. difficile clinical ... -
Integrating conflict, lobbying, and compliance to predict the sustainability of natural resource use
(The Resilience Alliance, 2020-06)Predictive models are sorely needed to guide the management of harvested natural resources worldwide, yet existing frameworks fail to integrate the dynamic and interacting governance processes driving unsustainable use. ... -
Intensity enhancement of ferromagnetic resonance modes in exchange coupled magnetic multilayers
(IOP PUBLISHING LTD, 2020)In this work, the ferromagnetic resonance characteristics of a NiFeCu/Non-magnetic(NM)/NiFe/NM/CoFe/NM/Co multilayer is studied from a theoretical point of view, and comparisons with the ferromagnetic resonance of a ... -
Interaction of supported ionic liquids phases onto copper nanoparticles: A DFT study
(Elsevier, 2020-07-15)The interaction between Supported Ionic Liquids Phases (SILPs) based on triazole and copper nanoparticles was investigated using density functional theory calculations. Three triazolium cations (T1(+), T2(+), and T3(+)) ... -
Intercepted journeys: Associations between migration and mobility experiences and depressive symptoms among substance using migrants at the Mexico-Guatemala border
(ROUTLEDGE JOURNALS, 2021-01)Substance use and depressive psychiatric symptoms have been associated with migration and mobility. The Mexico-Guatemala border is a key transit point for internal, regional, and international migration flows. However, ... -
Intergenerational Pathogen-Induced Diapause in Caenorhabditis elegans Is Modulated by mir-243
(Chile. Universidad Mayor, 2020)The interaction and communication between bacteria and their hosts modulate many aspects of animal physiology and behavior. Dauer entry as a response to chronic exposure to pathogenic bacteria in Caenorhabditis elegans is ... -
Interindividual responses to different exercise stimuli among insulin-resistant women
(WILEY, 2018)We aimed to investigate which among 20 cardiometabolic and performance outcomes do and do not respond to high-intensity interval training (HIT), resistance training (RT), or concurrent training (CT) in insulin-resistant ... -
Interleukin-17-induced neutrophil extracellular traps mediate resistance to checkpoint blockade in pancreatic cancer
(Rockefeller University Press, 2020-12)Pancreatic ductal adenocarcinoma (PDAC) remains a lethal malignancy with an immunosuppressive microenvironment that is resistant to most therapies. IL17 is involved in pancreatic tumorigenesis, but its role in invasive ... -
Interleukin-35 inhibits alveolar bone resorption by modulating the Th17/Treg imbalance during periodontitis
(Blackwell Munksgaard, 2020-04)Aim T lymphocytes play a central role during the pathogenesis of periodontitis, and the imbalance between the pathogenic T-helper type 17 (Th17) and protective T-regulatory (Treg) lymphocytes determines the tooth-supporting ... -
Intermediate-Salinity Systems at High Altitudes in the Peruvian Andes Unveil a High Diversity and Abundance of Bacteria and Viruses
(MDPI, 2019)Intermediate-salinity environments are distributed around the world. Here, we present a snapshot characterization of two Peruvian thalassohaline environments at high altitude, Maras and Acos, which provide an excellent ... -
International meeting on sarcoptic mange in wildlife, June 2018, Blacksburg, Virginia, USA
(BMC, 2018)Sarcoptic mange is a globally distributed disease caused by the burrowing mite Sarcoptes scabiei, which also causes scabies in humans. A wide and increasing number of wild mammal species are reported to be susceptible to ... -
Interoceptive Insular Cortex Mediates Both Innate Fear and Contextual Threat Conditioning to Predator Odor
(FRONTIERS MEDIA SA, 2020)The insular cortex (IC), among other brain regions, becomes active when humans experience fear or anxiety. However, few experimental studies in rats have implicated the IC in threat responses. We have recently reported ... -
Interplay between rotational work shift and high altitude-related chronic intermittent hypobaric hypoxia on cardiovascular health and sleep quality in Chilean miners
(Taylor and Francis Ltd., 2020-10)Mining activities expose workers to diverse working conditions, rotational shifts and high altitude-related hypobaric hypoxia. Separately, each condition has been reported having a negative impact on miners' health risk; ... -
Interspecific recognition in Chilean parabiotic ant species
(CIENCIAS, 2003)In Chile, Camponotus morosus and Solenopsis gayi sometimes co-inhabit a single nest, seemingly in a parabiotic association. To elucidate the nature of this association we conducted behavioural tests that measured aggression ... -
Intestinal epithelial cell-specific RAR alpha depletion results in aberrant epithelial cell homeostasis and underdeveloped immune system
(NATURE PUBLISHING GROUP, 2018)Retinoic acid (RA), a dietary vitamin A metabolite, is crucial in maintaining intestinal homeostasis. RA acts on intestinal leukocytes to modulate their lineage commitment and function. Although the role of RA has been ...