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Interoceptive Insular Cortex Mediates Both Innate Fear and Contextual Threat Conditioning to Predator Odor
(FRONTIERS MEDIA SA, 2020)The insular cortex (IC), among other brain regions, becomes active when humans experience fear or anxiety. However, few experimental studies in rats have implicated the IC in threat responses. We have recently reported ... -
Interplay between rotational work shift and high altitude-related chronic intermittent hypobaric hypoxia on cardiovascular health and sleep quality in Chilean miners
(Taylor and Francis Ltd., 2020-10)Mining activities expose workers to diverse working conditions, rotational shifts and high altitude-related hypobaric hypoxia. Separately, each condition has been reported having a negative impact on miners' health risk; ... -
Interspecific recognition in Chilean parabiotic ant species
(CIENCIAS, 2003)In Chile, Camponotus morosus and Solenopsis gayi sometimes co-inhabit a single nest, seemingly in a parabiotic association. To elucidate the nature of this association we conducted behavioural tests that measured aggression ... -
Intestinal epithelial cell-specific RAR alpha depletion results in aberrant epithelial cell homeostasis and underdeveloped immune system
(NATURE PUBLISHING GROUP, 2018)Retinoic acid (RA), a dietary vitamin A metabolite, is crucial in maintaining intestinal homeostasis. RA acts on intestinal leukocytes to modulate their lineage commitment and function. Although the role of RA has been ... -
Intestinal epithelial cell-specific RARa depletion results in aberrant epithelial cell homeostasis and underdeveloped immune system (vol 12, pg 580, 2019)
(NATURE PUBLISHING GROUP, 2019)Sin resumen -
Intestinal isosporiasis in patients with acquired immunodeficiency syndrome (AIDS). Pathologic diagnosis in small intestinal mucosal biopsies
(ELSEVIER SCIENCE INC, 2018)Highlights •The diagnosis of isosporiasis in AIDS patients requires tissue analysis.•The differential diagnosis of isosporiasis in small intestinal biopsies includes other coccidiosis and microsporidiosis.•The pathologic ... -
Intranasal oxytocin increases respiratory rate and reduces obstructive event duration and oxygen desaturation in obstructive sleep apnea patients: a randomized double blinded placebo controlled study
(Elsevier, 2020-10)Background: Activation of the oxytocin network has shown benefits in animal models of Obstructive Sleep Apnea (OSA) as well as other cardiorespiratory diseases. We sought to determine if nocturnal intranasal oxytocin ... -
Intratask Variability As a Correlate for DRD4 and SLC6A3 Variants: A Pilot Study in ADHD
(CIENCIAS, 2015)Behavioral variability may be an ADHD key feature. Currently used ex-Gaussian/Fast Fourier Transform analyses characterize general distribution and oscillatory/rhythmic components of performance but are unable to demonstrate ... -
Invasion dynamics of the European bumblebee Bombus terrestris in the southern part of South America
(NATURE PORTFOLIO, 2021-07-27)Invasive species are one of the main biodiversity loss drivers. Some species can establish and thrive in novel habitats, impacting local communities, as is the case of managed pollinators. In this regard, an invasive ... -
Invasive American Mink: Linking Pathogen Risk Between Domestic and Endangered Carnivores
(CIENCIAS, 2014)Infectious diseases, in particular canine distemper virus (CDV), are an important threat to the viability of wild carnivore populations. CDV is thought to be transmitted by direct contact between individuals; therefore, ... -
Invasive fungal infections in Chile: a multicenter study of fungal prevalence and susceptibility during a 1-year period
(CIENCIAS, 2004)During the first year of an ongoing surveillance program of invasive fungal infections (IFI) a total of 130 patients (56% male) with fungal strains isolated from blood and other sterile sites were reported from 13 hospitals ... -
Inverse Relationship Between Alzheimer's Disease and Cancer: How Immune Checkpoints Might Explain the Mechanisms Underlying Age-Related Diseases
(IOS PRESS, 2020)Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the adult population. There is evidence of an inverse epidemiological relationship between AD and cancer, another prevalent age-related disease. ... -
Investigating how perceived risk and availability of marijuana relate to marijuana use among adolescents in Argentina, Chile, and Uruguay over time
(ELSEVIER IRELAND LTD, 2019)Aims: Amid changing marijuana policies in the Southern Cone, we examined relationships between marijuana related risk factors and marijuana use among adolescents in Argentina, Chile, and Uruguay from 2001 to 2016. Methods: ... -
Involvement of specific laminins and nidogens in the active remodeling of the basal lamina of labial salivary glands from patients with Sjogren's syndrome
(CIENCIAS, 2006)OBJECTIVE: To investigate remodeling of the basal lamina of labial salivary glands (LSGs) from patients with Sjögren's syndrome (SS) by analyzing the expression of specific components that participate in its assembly and ... -
Involvement of the food industry in nutrition conferences in Latin America and the Caribbean
(Cambridge University Press, 2021-04)Objective: Identify and characterise the food industry's involvement in nutrition and dietetics national and regional events in Latin America and the Caribbean. Design: Between February and April 2020, we conducted desk-based ... -
Ion implantation in nanodiamonds: size effect and energy dependence
(NATURE PUBLISHING GROUP, 2018)Nanoparticles are ubiquitous in nature and are increasingly important for technology. They are subject to bombardment by ionizing radiation in a diverse range of environments. In particular, nanodiamonds represent a variety ... -
IRE1 alpha governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A
(NATURE PUBLISHING GROUP, 2018)Maintenance of endoplasmic reticulum (ER) proteostasis is controlled by a signalling network known as the unfolded protein response (UPR). Here, we identified filamin A as a major binding partner of the ER stress transducer ... -
IRE1α RIDD activity induced under ER stress drives neuronal death by the degradation of 14-3-3 θ mRNA in cortical neurons during glucose deprivation
(SPRINGER NATURE, 2021-06-03)Altered protein homeostasis is associated with neurodegenerative diseases and acute brain injury induced under energy depletion conditions such as ischemia. The accumulation of damaged or unfolded proteins triggers the ...