Listar Centro de Investigación en Genómica y Bioinformática (CGB) por fecha de publicación
Mostrando ítems 21-40 de 80
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Effect of CO2 Concentration on Uptake and Assimilation of Inorganic Carbon in the Extreme Acidophile Acidithiobacillus ferrooxidans
(FRONTIERS MEDIA SA, 2019)This study was motivated by surprising gaps in the current knowledge of microbial inorganic carbon (Ci) uptake and assimilation at acidic pH values (pH < 3). Particularly striking is the limited understanding of the ... -
ATP6V(0)d2 controls Leishmania parasitophorous vacuole biogenesis via cholesterol homeostasis
(PUBLIC LIBRARY SCIENCE, 2019)V-ATPases are part of the membrane components of pathogen-containing vacuoles, although their function in intracellular infection remains elusive. In addition to organelle acidification, V-ATPases are alternatively implicated ... -
Non-lysosomal Activation in Macrophages of Atlantic Salmon (Salmo salar) After Infection With Piscirickettsia salmonis
(FRONTIERS MEDIA SA, 2019)Piscirickettsia salmonis is a facultative intracellular pathogen and etiological agent of the systemic disease salmonid rickettsial septicemia. It has been suggested that P salmonis is able to survive in host macrophages, ... -
Uncovering the Mechanisms of Halotolerance in the Extremely Acidophilic Members of the Acidihalobacter Genus Through Comparative Genome Analysis
(FRONTIERS MEDIA SA, 2019)There are few naturally occurring environments where both acid and salinity stress exist together, consequently, there has been little evolutionary pressure for microorganisms to develop systems that enable them to deal ... -
Identification of functional signatures in the metabolism of the three cellular domains of life
(PUBLIC LIBRARY SCIENCE, 2019)In order to identify common and specific enzymatic activities associated with the metabolism of the three cellular domains of life, the conservation and variations between the enzyme contents of Bacteria, Archaea, and ... -
Signal peptide recognition in Trypanosoma cruzi GP82 adhesin relies on its localization at protein N-terminus
(NATURE PUBLISHING GROUP, 2019)Trypanosoma cruzi, the causative agent of Chagas disease, has a dense coat of GPI-anchored virulence factors. T. cruzi GPI-anchored adhesin GP82 is encoded by a repertoire of transcripts containing several in-frame initiation ... -
Identification and Unusual Properties of the Master Regulator FNR in the Extreme Acidophile Acidithiobacillus ferrooxidans
(FRONTIERS MEDIA SA, 2019)The ability to conserve energy in the presence or absence of oxygen provides a metabolic versatility that confers an advantage in natural ecosystems. The switch between alternative electron transport systems is controlled ... -
Thinning alters the expression of the PpeSUT1 and PpeSUT4 sugar transporter genes and the accumulation of translocated sugars in the fruits of an early season peach variety
(Chile. Universidad Mayor, 2019)Thinning is an agronomic practice that consists in the removal of a certain number of fruits, thereby altering the source-sink equilibrium in the tree and favoring carbon allocation to the remaining fruits. If thinning is ... -
Cátedras del Futuro: ¿Cambiemos el mundo? Un genoma a la vez
(Chile. Universidad Mayor, 2019-06-26)La segunda fecha de este ciclo de conferencias tuvo como protagonista al Dr. Patricio Manque, Vicerrector de Investigación, quien presenta la charla “¿Cambiemos el mundo? Un genoma a la vez”. La jornada, llevada a cabo el ... -
Cátedras del Futuro: C. elegans: ¿cómo un gusano nos puede ayudar a comprender mejor enfermedades como el Parkinson y el Alzheimer?
(Chile. Universidad Mayor, 2019-09-05)En una nueva fecha del ciclo de charlas “Cátedras del Futuro”, la Dra. Andrea Calixto, académica del Centro de Genómica y Bioinformática U. Mayor, que presentó los resultados de las investigaciones que durante 4 años ha ... -
Engineering a single-chain antibody against Trypanosoma cruzi metacyclic trypomastigotes to block cell invasion
(Chile. Universidad Mayor, 2019-10-16)Trypanosoma cruzi is a flagellate protozoan pathogen that causes Chagas disease. Currently there is no preventive treatment and the efficiency of the two drugs available is limited to the acute phase. Therefore, there is ... -
The protein architecture in Bacteria and Archaea identifies a set of promiscuous and ancient domains
(Public Library of Science, 2019-12-19)In this work, we describe a systematic comparative genomic analysis of promiscuous domains in genomes of Bacteria and Archaea. A quantitative measure of domain promiscuity, the weighted domain architecture score (WDAS), ... -
Inhibitory effect of serotype a of Aggregatibacter actinomycetemcomitans on the increased destructive potential of serotype b
(WILEY, 2020)Objective The serotype b of Aggregatibacter actinomycetemcomitans (A. actinomycetemcomitans) induces higher cytokine production in dendritic cells (DCs) compared with the other serotypes. However, this increased immunostimulatory ... -
NOTCH3 Gene Mutation in a Chilean Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy Family
(ELSEVIER, 2020)Introduction: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a rare hereditary stroke disorder caused by mutations in the NOTCH3 gene. We report the first Chilean ... -
Evaluation of the Abundance of DNA-Binding Transcription Factors in Prokaryotes
(MDPI, 2020)The ability of bacteria and archaea to modulate metabolic process, defensive response, and pathogenic capabilities depend on their repertoire of genes and capacity to regulate the expression of them. Transcription factors ... -
Transcriptomic analysis at organ and time scale reveals gene regulatory networks controlling the sulfate starvation response ofSolanum lycopersicum
(Chile. Universidad Mayor, 2020)Background Sulfur is a major component of biological molecules and thus an essential element for plants. Deficiency of sulfate, the main source of sulfur in soils, negatively influences plant growth and crop yield. The ... -
Understanding gold toxicity in aerobically-grown Escherichia coli
(Chile. Universidad Mayor, 2020)Background There is an emerging field to put into practice new strategies for developing molecules with antimicrobial properties. In this line, several metals and metalloids are currently being used for these purposes, ... -
Partitioning beta-diversity reveals that invasions and extinctions promote the biotic homogenization of Chilean freshwater fish fauna
(Chile. Universidad Mayor, 2020)Aim Exotic species' introductions together with extinction of native species represent the main mechanisms driving biotic homogenization of freshwater fish assemblages around the world. While generally ichtyofaunistic ... -
A dynamic portal for a community-driven, continuously updated classification of Fungi and fungus-like organisms: outlineoffungi.org
(Chile. Universidad Mayor, 2020)The website http://outlineoffungi.org, is launched to provide a continuous up-to-date classification of the kingdom Fungi (including fossil fungi) and fungus-like taxa. This is based on recent publications and on the outline ... -
Outline of Fungi and fungus-like taxa
(Guizhou Key Laboratory of Agricultural Biotechnology, 2020)This article provides an outline of the classification of the kingdom Fungi (including fossil fungi. i.e. dispersed spores, mycelia, sporophores, mycorrhizas). We treat 19 phyla of fungi. These are Aphelidiomycota, Ascomycota, ...