ListarINVESTIGACIÓN por tema "Multidisciplinary Sciences"
Mostrando ítems 21-34 de 34
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Phenology determines the robustness of plant-pollinator networks
(NATURE PUBLISHING GROUP, 2018)Plant-pollinator systems are essential for ecosystem functioning, which calls for an understanding of the determinants of their robustness to environmental threats. Previous studies considering such robustness have focused ... -
Pleione: A tool for statistical and multi-objective calibration of Rule-based models
(NATURE PUBLISHING GROUP, 2019)Mathematical models based on Ordinary Differential Equations (ODEs) are frequently used to describe and simulate biological systems. Nevertheless, such models are often difficult to understand. Unlike ODE models, Rule-Based ... -
RIP-MD: a tool to study residue interaction networks in protein molecular dynamics
(PEERJ INC, 2018)Protein structure is not static; residues undergo conformational rearrangements and, in doing so, create, stabilize or break non-covalent interactions. Molecular dynamics (MD) is a technique used to simulate these movements ... -
Seabird and pinniped shape soil bacterial communities of their settlements in Cape Shirreff, Antarctica
(PUBLIC LIBRARY SCIENCE, 2019)Seabirds and pinnipeds play an important role in biogeochemical cycling by transferring nutrients from aquatic to terrestrial environments. Indeed, soils rich in animal depositions have generally high organic carbon, ... -
Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation
(NATURE PUBLISHING GROUP, 2019)RIPK1 regulates cell death and inflammation through kinase-dependent and -independent mechanisms. As a scaffold, RIPK1 inhibits caspase-8-dependent apoptosis and RIPK3/MLKL-dependent necroptosis. As a kinase, RIPK1 ... -
Signal peptide recognition in Trypanosoma cruzi GP82 adhesin relies on its localization at protein N-terminus
(NATURE PUBLISHING GROUP, 2019)Trypanosoma cruzi, the causative agent of Chagas disease, has a dense coat of GPI-anchored virulence factors. T. cruzi GPI-anchored adhesin GP82 is encoded by a repertoire of transcripts containing several in-frame initiation ... -
Species traits and network structure predict the success and impacts of pollinator invasions
(NATURE PUBLISHING GROUP, 2018)Species invasions constitute a major and poorly understood threat to plant-pollinator systems. General theory predicting which factors drive species invasion success and subsequent effects on native ecosystems is particularly ... -
Temporal and spatial dynamics of Bacteria, Archaea and protists in equatorial coastal waters
(NATURE PUBLISHING GROUP, 2019)Singapore, an equatorial island in South East Asia, is influenced by a bi-annual reversal of wind directions which defines two monsoon seasons. We characterized the dynamics of the microbial communities of Singapore coastal ... -
The fecal, oral, and skin microbiota of children with Chagas disease treated with benznidazole
(PUBLIC LIBRARY SCIENCE, 2019)Background Chagas disease is still prevalent in rural areas of South America. In endemic areas of Bolivia, school children are screened for the program of Chagas disease eradication of the Ministry of Health, and positive ... -
The fecal, oral, and skin microbiota of children with Chagas disease treated with benznidazole (vol 14, e0212593, 2019)
(PUBLIC LIBRARY SCIENCE, 2019)Sin resumen -
The Metabolomic Signature of Opa1 Deficiency in Rat Primary Cortical Neurons Shows Aspartate/Glutamate Depletion and Phospholipids Remodeling
(NATURE PUBLISHING GROUP, 2019)Pathogenic variants of OPA1, which encodes a dynamin GTPase involved in mitochondrial fusion, are responsible for a spectrum of neurological disorders sharing optic nerve atrophy and visual impairment. To gain insight on ... -
Transcriptomics reveals a cross-modulatory effect between riboflavin and iron and outlines responses to riboflavin biosynthesis and uptake in Vibrio cholerae
(NATURE PUBLISHING GROUP, 2018)Vibrio cholerae, a pandemic diarrheagenic bacterium, is able to synthesize the essential vitamin riboflavin through the riboflavin biosynthetic pathway (RBP) and also to internalize it through the RibN importer. In bacteria, ... -
Uptake and persistence of bacterial magnetite magnetosomes in a mammalian cell line: Implications for medical and biotechnological applications
(PUBLIC LIBRARY SCIENCE, 2019)Magnetotactic bacteria biomineralize intracellular magnetic nanocrystals surrounded by a lipid bilayer called magnetosomes. Due to their unique characteristics, magnetite magnetosomes are promising tools in Biomedicine. ... -
Whole Genome Sequence, Variant Discovery and Annotation in Mapuche-Huilliche Native South Americans
(NATURE PUBLISHING GROUP, 2019)Whole human genome sequencing initiatives help us understand population history and the basis of genetic diseases. Current data mostly focuses on Old World populations, and the information of the genomic structure of Native ...