Mostrando ítems 1101-1120 de 1852

    • Contribution of type 2 diabetes to all-cause mortality, cardiovascular disease incidence and cancer incidence in white Europeans and South Asians: findings from the UK Biobank population-based cohort study 

      Celis-Morales, Carlos [Univ Mayor, Ctr Res Exercise Physiol CIFE, Santiago, Chile]; Muilwijk, Mirthe; Ho, Frederick; Waddell, Heather; Sillars, Anne; Welsh, Paul; Iliodromiti, Stamatina; Brown, Rosemary; Ferguson, Lyn; Stronks, Karien; van Valkengoed, Irene; Pell, Jill P.; Gray, Stuart Robert; Gill, Jason Martin Regnald; Sattar, Naveed (BMJ PUBLISHING GROUP, 2019)
      Objective To investigate whether the health implications of having type 2 diabetes (T2D) were different in South Asian compared with white European participants. Research design and methods Prospective data from UK Biobank ...
    • Physical activity and sedentary behaviours are associated with cognitive impairment in Chilean older adults 

      Celis-Morales, Carlos [Univ Mayor, CIFE, Santiago, Chile]; Poblete-Valderrama, Felipe; Flores Rivera, Carol; Petermann-Rocha, Fanny; María Leiva, Ana; Adela Martínez-Sanguinetti, Maria; Troncoso, Claudia; Mardones, Lorena; Villagrán, Marcelo; Nazar, Gabriela; Ulloa, Natalia; Martorell, Miquel; Díaz-Martínez, Ximena; Lanuza, Fabian; Garrido-Méndez, Alex (SOC MEDICA SANTIAGO, 2019)
      Background: Lifestyle factors could promote healthy ageing. Aim: To investigate the association between physical activity (PA), sedentary behavior and cognitive impairment in Chilean older adults. Material and Methods: We ...
    • A new piece in the genetic puzzle of obesity 

      Celis-Morales, Carlos [Univ Mayor, CIFE, Santiago, Chile]; Villagrán, Marcelo; Petermann-Rocha, Fanny; Adela Martínez-Sanguinetti, Maria (SOC MEDICA SANTIAGO, 2019)
      Sin resumen
    • Scientific physicians in crisis? In Memoriam Dr. Jorge Mardones Restat 

      Rios, Juvenal A. [Univ Mayor, Fac Ciencias, Programas Futuro, Santiago, Chile]; Francisca Barake, M.; Labbe, Tomás P. (SOC MEDICA SANTIAGO, 2019)
      Sin resumen
    • IL-22-expressing CD4(+)AhR(+) T lymphocytes are associated with RANKL-mediated alveolar bone resorption during experimental periodontitis 

      Cortez, Cristián [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Santiago, Chile]; Cortés, Bastián I. [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Santiago, Chile]; Vicencio, Emiliano [Univ Mayor, Ctr Genom & Bioinformat, Fac Sci, Santiago, Chile]; Monasterio, Gustavo; Budini, Víctoria; Fernández, Baltasar; Castillo, Francisca; Rojas, Carolina; Alvarez, Carla; Cafferata, Emilio A.; Vernal, Rolando (WILEY, 2019)
      Background and Objective Over the past few years, the importance of interleukin-22 (IL-22) and T-helper (Th)22 lymphocytes in the pathogenesis of periodontitis has become apparent; however, there are still aspects that are ...
    • Dynamics of erosion processes in the tropics: a dendrogeomorphological approach in an Ultisol of southeastern Brazil 

      Alejandro Roig, Fidel [Univ Mayor, Fac Ciencias, Hemera Ctr Observac Tierra, Santiago, Chile]; Bovi, Renata Cristina; Chartier, Marcelo Pablo; Tomazello Filho, Mario; Castillo, Virginia Dominguez; Cooper, Miguel (SPRINGER, 2019)
      Background and aims Soil erosion is one of the degradation processes that historically has caused great impacts on agricultural activities and the environment. It is responsible for soil loss, reduced productivity and ...
    • Maximal Fat Oxidation by Hear Rate Variability in Physically Active Subjects 

      Sáez-Olivares, Sebastián [Univ Mayor, Fac Sci]; Pino-Zuniga, Johanna; Olivares-Galvez, Mariela; Cancino-López, Jorge (INST NACL EDUCACION FISICA CATALUNA, 2019)
      Introduction: the objective of this study is to identify the intensity of the maximal fat oxidation point (Fatmax) and its relationship to the first heart rate variability threshold (HRVT1). Subjects and methods. 23 subjects ...
    • One in five deaths are associated with an unhealthy diet worldwide: what is the current scenario in Chile? 

      Celis-Morales, Carlos [Univ Mayor, CIFE, Santiago, Chile]; Adela Martínez-Sanguinetti, Maria; María Leiva, Ana; Petermann-Rocha, Fanny; Villagrán, Marcelo; Troncoso-Pantoja, Claudia (SOC CHILENA NUTRICION, BROMATOLOGIA & TOXICOLOGIA, 2019)
      Sin resumen
    • Ketogenic diet ameliorates dysferlinopathy phenotype in Dysf-/-mice by promoting mitochondrial function 

      Cardenas, J. [Univ Mayor, Fac Sci, Santiago, Chile]; Basualto-Alarcón, C.; Caviedes, P.; Bevilacqua, J. (PERGAMON-ELSEVIER SCIENCE LTD, 2019)
      Sin resumen
    • Curvularia spicifera 

      Madrid, Hugo; Cárcamo, Carolina [Univ Mayor, Fac Ciencias, Ctr Genom & Bioinformat, Santiago, Chile]; Cárcamo, Carolina; Tapia, Cecilia (SOC CHILENA INFECTOLOGIA, 2019)
      Sin resumen
    • Factors associated with cognitive impairment in older adults in Chile 

      Celis-Morales, Carlos [Univ Mayor, CIFE, Santiago, Chile]; Adela Martínez-Sanguinetti, Maria; María Leiva, Ana; Petermann-Rocha, Fanny; Troncoso-Pantoja, Claudia; Villagrán, Marcelo; Lanuza-Rilling, Fabian; Nazar, Gabriela; Poblete-Valderrama, Felipe; Díaz-Martínez, Ximena (SOC MEDICA SANTIAGO, 2019)
      Background: The risk factors for the development of cognitive impairment are not well known. Aim: To identify socio-demographic, lifestyle and health-related factors associated with cognitive impairment in older Chilean ...
    • Association of the TCF7L2 (RS7903146) genotype with adiposity and metabolic markers in the Chilean adult population 

      Celis-Morales, Carlos [Univ Mayor, CIFE, Santiago, Chile]; Petermann-Rocha, Fanny; Lasserre-Laso, Nicole; Villagrán, Marcelo; Mardones, Lorena; Adela Martínez, Maria; María Leiva, Ana; Ulloa, Natalia (SOC MEDICA SANTIAGO, 2019)
      Background: Type 2 diabetes etiology has a strong genetic component. More than 20 genetic variants have been associated with diabetes and other metabolic markers. However, the polymorphism rs7903146 of the TCF7L2 gene has ...
    • Coagulation Factor Xa Promotes Solid Tumor Growth, Experimental Metastasis and Endothelial Cell Activation 

      Erices, Rafaela [Univ Mayor, Vicerrectoria Invest] (MDPI, 2019)
      Hypercoagulable state is linked to cancer progression; however, the precise role of the coagulation cascade is poorly described. Herein, we examined the contribution of a hypercoagulative state through the administration ...
    • Nanopore Sequencing Significantly Improves Genome Assembly of the Protozoan Parasite Trypanosoma cruzi 

      Iraola, Gregorio [Univ Mayor, Ctr Integrat Biol, Santiago, Chile]; Díaz-Viraque, Florencia; Pita, Sebastián; Greif, Gonzalo; Moreira De Souza, Rita de Cassia; Robello, Carlos (OXFORD UNIV PRESS, 2019)
      Chagas disease was described by Carlos Chagas, who first identified the parasite Trypanosoma cruzi from a 2-year-old girl called Berenice. Many T. cruzi sequencing projects based on short reads have demonstrated that genome ...
    • Adherence to physical activity recommendations across age categories: Findings from the 2009-2010 Chilean National Health Survey 

      Celis-Morales, Carlos [Univ Mayor, CIFE, Santiago, Chile]; Garrido-Méndez, Alex; Concha-Cisrnas, Yeny; Rocha, Fanny Petermann; Díaz-Martínez, Ximena; María Leiva, Ana; Troncoso, Claudia; Adela Martínez, Maria; Salas-Bravo, Arlos; Alvarez, Cristián; Ramírez-Campillo, Rodrigo; Cristi-Montero, Carlos; Rodríguez, Fernando; Iturra-González, Lose A. (SOC CHILENA NUTRICION, BROMATOLOGIA & TOXICOLOGIA, 2019)
      Although physical activity (PA) is a protective factor against non-communicable diseases, there is an important proportion of the population who do not meet PA guidelines. Our aim was to investigate how adherence to PA ...
    • c-Jun N-terminal kinase (JNK)-dependent internalization and Rab5-dependent endocytic sorting mediate long-distance retrograde neuronal death induced by axonal BDNF-p75 signaling 

      Court, F. A. [Univ Mayor, Fac Sci, Ctr Integrat Biol, Santiago, Chile]; Escudero, C. A.; Cabeza, C.; Moya-Alvarado, G.; Maloney, M. T.; Flores, C. M.; Wu, C.; Mobley, W. C.; Bronfman, F. C. (NATURE PUBLISHING GROUP, 2019)
      During the development of the sympathetic nervous system, signals from tropomyosin-related kinase receptors (Trks) and p75 neurotrophin receptors (p75) compete to regulate survival and connectivity. During this process, ...
    • Cognitive impairment in heart failure is associated with altered Wnt signaling in the hippocampus 

      Andrade, David C. [Univ Mayor, Ctr Invest Fisiol Ejercicio, Santiago, Chile]; Toledo, Camilo; Lucero, Claudia; Díaz, Hugo S.; Schwarz, Karla G.; Pereyra, Katherin V.; Arce-Alvarez, Alexis; López, Nicolás A.; Martínez, Milka; Inestrosa, Nibaldo C.; Del Rio, Rodrigo (IMPACT JOURNALS LLC, 2019)
      Age represents the highest risk factor for death due to cardiovascular disease. Heart failure (HF) is the most common cardiovascular disease in elder population and it is associated with cognitive impairment (CI), diminishing ...
    • Oral contraceptive use and depression among adolescents 

      Keyes, Katherine M. [Univ Mayor, Ctr Res Soc & Hlth, Santiago, Chile]; McKetta, Sarah (ELSEVIER SCIENCE INC, 2019)
      Purpose: Depression is a prevalent health problem affecting U.S. women. Oral contraceptive pills (OCPs) are commonly used for pregnancy prevention, and evidence is mixed regarding any increased risk for incident depression ...
    • Rostral ventrolateral medullary catecholaminergic neurones mediate irregular breathing pattern in volume overload heart failure rats 

      Andrade, David C. [Univ Mayor, Ctr Invest Fisiol Ejercicio, Santiago, Chile]; Toledo, Camilo; Díaz, Hugo S.; Pereyra, Katherin V.; Schwarz, Karla G.; Díaz-Jara, Esteban; Oliveira, Luiz M.; Takakura, Ana C.; Moreira, Thiago S.; Schultz, Harold D.; Marcus, Noah J.; Del Rio, Rodrigo (WILEY, 2019)
      Key points A strong association between disordered breathing patterns, elevated sympathetic activity, and enhanced central chemoreflex drive has been shown in experimental and human heart failure (HF). The aim of this study ...
    • Prescription drug monitoring programs operational characteristics and fatal heroin poisoning 

      Castillo-Carniglia, Alvaro [Univ Mayor, Fac Humanidades, Soc & Hlth Res Ctr, Santiago, Chile]; Martins, Silvia S.; Ponicki, William; Smith, Nathan; Rivera-Aguirre, Ariadne; Davis, Corey S.; Fink, David S.; Henry, Stephen G.; Marshall, Brandon D. L.; Gruenewald, Paul; Cerda, Magdalena (ELSEVIER, 2019)
      Background: Prescription drug monitoring programs (POMP), by reducing access to prescribed opioids (POs), may contribute to a policy environment in which some people with opioid dependence are at increased risk for ...


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