Listar Centro de Investigación en Genómica y Bioinformática (CGB) por título
Mostrando ítems 64-80 de 80
-
Signal peptide recognition in Trypanosoma cruzi GP82 adhesin relies on its localization at protein N-terminus
(NATURE PUBLISHING GROUP, 2019)Trypanosoma cruzi, the causative agent of Chagas disease, has a dense coat of GPI-anchored virulence factors. T. cruzi GPI-anchored adhesin GP82 is encoded by a repertoire of transcripts containing several in-frame initiation ... -
SinEx DB 2.0 update 2020: database for eukaryotic single-exon coding sequences
(Oxford University Press, 2021-01-28)Single-exon coding sequences (CDSs), also known as 'single-exon genes' (SEGs), are defined as nuclear, protein-coding genes that lack introns in their CDSs. They have been studied not only to determine their origin and ... -
Single-Nucleotide Polymorphisms (SNP) Mining and Their Effect on the Tridimensional Protein Structure Prediction in a Set of Immunity-Related Expressed Sequence Tags (EST) in Atlantic Salmon (Salmo salar)
(Frontiers Media S.A., 2020-02-27)Single-nucleotide polymorphisms (SNPs) are single genetic code variations considered one of the most common forms of nucleotide modifications. Such SNPs can be located in genes associated to immune response and, therefore, ... -
SMZ/SNZ and gibberellin signaling are required for nitrate-elicited delay of flowering time in Arabidopsis thaliana
(OXFORD UNIV PRESS, 2018)The reproductive success of plants largely depends on the correct programming of developmental phase transitions, particularly the shift from vegetative to reproductive growth. The timing of this transition is finely ... -
TGA class II transcription factors are essential to restrict oxidative stress in response to UV-B stress in Arabidopsis
(OXFORD UNIV PRESS, 2021-02-27)Plants possess a robust metabolic network for sensing and controlling reactive oxygen species (ROS) levels upon stress conditions. Evidence shown here supports a role for TGA class II transcription factors as critical ... -
The Microbial Composition in Circumneutral Thermal Springs from Chignahuapan, Puebla, Mexico Reveals the Presence of Particular Sulfur-Oxidizing Bacterial and Viral Communities
(MDPI AG, 2020-11)Terrestrial thermal springs are widely distributed globally, and these springs harbor a broad diversity of organisms of biotechnological interest. In Mexico, few studies exploring this kind of environment have been described. ... -
The protein architecture in Bacteria and Archaea identifies a set of promiscuous and ancient domains
(Public Library of Science, 2019-12-19)In this work, we describe a systematic comparative genomic analysis of promiscuous domains in genomes of Bacteria and Archaea. A quantitative measure of domain promiscuity, the weighted domain architecture score (WDAS), ... -
Thinning alters the expression of the PpeSUT1 and PpeSUT4 sugar transporter genes and the accumulation of translocated sugars in the fruits of an early season peach variety
(Chile. Universidad Mayor, 2019)Thinning is an agronomic practice that consists in the removal of a certain number of fruits, thereby altering the source-sink equilibrium in the tree and favoring carbon allocation to the remaining fruits. If thinning is ... -
Tracing the phylogenetic history of the Crl regulon through the Bacteria and Archaea genomes
(BMC, 2019)Background: Crl, identified for curli production, is a small transcription factor that stimulates the association of the sigma(S) factor (RpoS) with the RNA polymerase core through direct and specific interactions, increasing ... -
Transcriptional profiling of embryos lacking the lipoprotein receptor SR-B1 reveals a regulatory circuit governing a neurodevelopmental or metabolic decision during neural tube closure
(BMC, 2018)Background: The high-density lipoprotein receptor SR-B1 mediates cellular uptake of several lipid species, including cholesterol and vitamin E. During early mouse development, SR-B1 is located in the maternal-fetal interface, ... -
Transcriptomic analysis at organ and time scale reveals gene regulatory networks controlling the sulfate starvation response ofSolanum lycopersicum
(Chile. Universidad Mayor, 2020)Background Sulfur is a major component of biological molecules and thus an essential element for plants. Deficiency of sulfate, the main source of sulfur in soils, negatively influences plant growth and crop yield. The ... -
Transient genome-wide interactions of the master transcription factor NLP7 initiate a rapid nitrogen-response cascade
(Nature Publishing Group, 2020-03-02)Dynamic reprogramming of gene regulatory networks (GRNs) enables organisms to rapidly respond to environmental perturbation. However, the underlying transient interactions between transcription factors (TFs) and genome-wide ... -
Uncovering the Mechanisms of Halotolerance in the Extremely Acidophilic Members of the Acidihalobacter Genus Through Comparative Genome Analysis
(FRONTIERS MEDIA SA, 2019)There are few naturally occurring environments where both acid and salinity stress exist together, consequently, there has been little evolutionary pressure for microorganisms to develop systems that enable them to deal ... -
Understanding gold toxicity in aerobically-grown Escherichia coli
(Chile. Universidad Mayor, 2020)Background There is an emerging field to put into practice new strategies for developing molecules with antimicrobial properties. In this line, several metals and metalloids are currently being used for these purposes, ... -
Unlocking Survival Mechanisms for Metal and Oxidative Stress in the Extremely Acidophilic, Halotolerant Acidihalobacter Genus
(MDPI Multidisciplinary Digital Publishing Institute, 2020-11-24)Microorganisms used for the biohydrometallurgical extraction of metals from minerals must be able to survive high levels of metal and oxidative stress found in bioleaching environments. The Acidihalobacter genus consists ... -
Whole Genome Sequence, Variant Discovery and Annotation in Mapuche-Huilliche Native South Americans
(NATURE PUBLISHING GROUP, 2019)Whole human genome sequencing initiatives help us understand population history and the basis of genetic diseases. Current data mostly focuses on Old World populations, and the information of the genomic structure of Native ... -
Whole-exome sequencing of oral epithelial dysplasia samples reveals an association with new genes
(SOCIEDADE BRASILEIRA DE PESQUISA ODONTOLOGICA, 2023-03-23)The genetic basis of oral epithelial (OED) is unknown, and there is no reliable method for evaluating the risk of malignant transformation. Somatic mutations are responsible for the transformation of dysplastic mucosa to ...