ListarINVESTIGACIÓN por tema "Multidisciplinary Sciences"
Mostrando ítems 1-20 de 34
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Abrogation of Stem Loop Binding Protein (Slbp) function leads to a failure of cells to transition from proliferation to differentiation, retinal coloboma and midline axon guidance deficits
(PUBLIC LIBRARY SCIENCE, 2019)Through forward genetic screening for mutations affecting visual system development, we identified prominent coloboma and cell-autonomous retinal neuron differentiation, lamination and retinal axon projection defects in ... -
Ankle perturbation generates bilateral alteration of knee muscle onset times after unilateral anterior cruciate ligament reconstruction
(PEERJ INC, 2018)Background. The aim of this study was to compare muscle activation onset times of knee muscles between the involved and uninvolved knee of patients with unilateral anterior cruciate ligament reconstruction (ACLR), and the ... -
c-Jun N-terminal kinase (JNK)-dependent internalization and Rab5-dependent endocytic sorting mediate long-distance retrograde neuronal death induced by axonal BDNF-p75 signaling
(NATURE PUBLISHING GROUP, 2019)During the development of the sympathetic nervous system, signals from tropomyosin-related kinase receptors (Trks) and p75 neurotrophin receptors (p75) compete to regulate survival and connectivity. During this process, ... -
Changes in belowground biodiversity during ecosystem development
(NATL ACAD SCIENCES, 2019)Belowground organisms play critical roles in maintaining multiple ecosystem processes, including plant productivity, decomposition, and nutrient cycling. Despite their importance, however, we have a limited understanding ... -
Climatic controls of decomposition drive the global biogeography of forest-tree symbioses
(NATURE PUBLISHING GROUP, 2019)The identity of the dominant root-associated microbial symbionts in a forest determines the ability of trees to access limiting nutrients from atmospheric or soil pools(1,2), sequester carbon(3,4) and withstand the effects ... -
Core non-coding RNAs of Piscirickettsia salmonis
(PUBLIC LIBRARY SCIENCE, 2018)Piscirickettsia salmonis, a fastidious Gram-negative intracellular facultative bacterium, is the causative agent o Piscirickettsiosis. P. salmonis has broad host range with a nearly worldwide distribution, causing significant ... -
Endoplasmic reticulum stress leads to accumulation of wild-type SOD1 aggregates associated with sporadic amyotrophic lateral sclerosis
(NATL ACAD SCIENCES, 2018)Abnormal modifications to mutant superoxide dismutase 1 (SOD1) are linked to familial amyotrophic lateral sclerosis (fALS). Misfolding of wild-type SOD1 (SOD1(WT)) is also observed in postmortem tissue of a subset of ... -
Global ecological predictors of the soil priming effect
(NATURE PUBLISHING GROUP, 2019)Identifying the global drivers of soil priming is essential to understanding C cycling in terrestrial ecosystems. We conducted a survey of soils across 86 globally-distributed locations, spanning a wide range of climates, ... -
High similarity in the microbiota of cold-water sponges of the Genus Mycale from two different geographical areas
(PEERJ INC, 2018)Sponges belonging to genus Mycale are common and widely distributed across the oceans and represent a significant component of benthic communities in term of their biomass, which in many species is largely composed by ... -
Hydroclimatic variations reveal differences in carbon capture in two sympatric conifers in northern Mexico
(PEERJ INC, 2019)Background. Forest ecosystems are considered among the largest terrestrial carbon sinks. The dynamics of forest carbon depend on where the carbon is stored and its responses to environmental factors, as well as the physiology ... -
Identification of functional signatures in the metabolism of the three cellular domains of life
(PUBLIC LIBRARY SCIENCE, 2019)In order to identify common and specific enzymatic activities associated with the metabolism of the three cellular domains of life, the conservation and variations between the enzyme contents of Bacteria, Archaea, and ... -
Integrated genomic epidemiology and phenotypic profiling of Clostridium difficile across intra-hospital and community populations in Colombia
(NATURE PUBLISHING GROUP, 2019)Clostridium difficile, the causal agent of antibiotic-associated diarrhea, has a complex epidemiology poorly studied in Latin America. We performed a robust genomic and phenotypic profiling of 53 C. difficile clinical ... -
Ion implantation in nanodiamonds: size effect and energy dependence
(NATURE PUBLISHING GROUP, 2018)Nanoparticles are ubiquitous in nature and are increasingly important for technology. They are subject to bombardment by ionizing radiation in a diverse range of environments. In particular, nanodiamonds represent a variety ... -
Knee sensorimotor control following anterior cruciate ligament reconstruction: A comparison between reconstruction techniques
(PUBLIC LIBRARY SCIENCE, 2018)The sensorimotor system helps to maintain functional joint stability during movement. After anterior cruciate ligament (ACL) injury and reconstruction, several sensorimotor deficits may arise, including altered proprioception ... -
Linoleic acid and stearic acid are biosynthetic precursors of (7Z,10Z)-7,10-hexadecadienal, the major component of the sex pheromone of Chilecomadia valdiviana (Lepidoptera: Cossidae)
(PUBLIC LIBRARY SCIENCE, 2019)The main pheromone compound of Chilecomadia valdiviana (Lepidoptera: Cossidae) has been recently identified as (7Z,10Z)-7,10-hexadecadienal. The biosynthesis of this pheromone compound showing attributes of both Type I and ... -
Maintaining close canopy cover prevents the invasion of Pinus radiata: Basic ecology to manage native forest invasibility
(PUBLIC LIBRARY SCIENCE, 2019)Pine invasion is a global threat that is occurring in native forests of diverse regions of the world. This process is arising in a scenario of rapid forest deforestation and degradation. Therefore, elucidate which forests ... -
Mat thickness associated with Didymosphenia geminata and Cymbella spp. in the southern rivers of Chile
(PEERJ INC, 2019)Didymosphenia geminata is a diatom that can alter aquatic systems. Several investigations have shown as chemical, and hydraulic factors have a great influence on the proliferation of D. geminata, but the study of other ... -
MLSTar: automatic multilocus sequence typing of bacterial genomes in R
(PEERJ INC, 2018)Multilocus sequence typing (MLST) is a standard tool in population genetics and bacterial epidemiology that assesses the genetic variation present in a reduced number of housekeeping genes (typically seven) along the genome. ... -
Multiple processes acting from local to large geographical scales shape bacterial communities associated with Phormidium (cyanobacteria) biofilms in French and New Zealand rivers
(NATURE PUBLISHING GROUP, 2018)River biofilms dominated by Phormidium (cyanobacteria) are receiving increased attention worldwide because of a recent expansion in their distribution and their ability to produce neurotoxins leading to animal mortalities. ... -
One-class land-cover classification using MaxEnt: the effect of modelling parameterization on classification accuracy
(PEERJ INC, 2019)Multiple-class land-cover classification approaches can be inefficient when the main goal is to classify only one or a few classes. Under this scenario one-class classification algorithms could be a more efficient alternative. ...