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Unraveling the role of motoneuron autophagy in ALS

Nassif, Melissa [Univ Mayor, Fac Sci, CIB, Santiago, Chile]; Valenzuela, Vicente; Hetz, Claudio (TAYLOR & FRANCIS INC, 2018)

In recent years, the role of autophagy in the pathogenesis of most neurodegenerative diseases has transitioned into a limbo of protective or detrimental effects. Genetic evidence indicates that mutations in autophagy-regulatory ...
Vitamin D Increases A beta 140 Plasma Levels and Protects Lymphocytes from Oxidative Death in Mild Cognitive Impairment Patients

SanMartin, Carol D. [Univ Mayor, Ctr Integrat Biol, Santiago, Chile]; Henríquez, Mauricio; Chacón, Carlos; Ponce, Daniela P.; Salech, Felipe; Rogers, Nicole K.; Behrens, María I. (BENTHAM SCIENCE PUBL LTD, 2018)

Background: Mild cognitive impairment (MCI) has an increased rate of progression to dementia. Alterations of some metabolic factors, such as deficiency of vitamin D, are a risk factor for cognitive deterioration. Vitamin ...