Browsing Centro de Investigación en Genómica y Bioinformática (CGB) by Title
Now showing items 1-20 of 80
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A balancing act: how plants integrate nitrogen and water signals
(Oxford University Press, 2020-07-25)Nitrogen (N) and water (W) are crucial inputs for plant survival as well as costly resources for agriculture. Given their importance, the molecular mechanisms that plants rely on to signal changes in either N or W status ... -
A decade later, reviewing floating marine debris in Northern Chilean Patagonia
(PERGAMON-ELSEVIER SCIENCE LTD, 2021-07-07)Floating marine debris (FMD) were abundantly reported in the Northern Chilean Patagonia in 2009 where seabased activities (mussel and salmon aquaculture) are responsible for most of them. Identifying the sources of FMD is ... -
A dynamic portal for a community-driven, continuously updated classification of Fungi and fungus-like organisms: outlineoffungi.org
(Chile. Universidad Mayor, 2020)The website http://outlineoffungi.org, is launched to provide a continuous up-to-date classification of the kingdom Fungi (including fossil fungi) and fungus-like taxa. This is based on recent publications and on the outline ... -
A HaloTag-TEV genetic cassette for mechanical phenotyping of proteins from tissues
(Nature Publishing Group, 2020-04-28)Single-molecule methods using recombinant proteins have generated transformative hypotheses on how mechanical forces are generated and sensed in biological tissues. However, testing these mechanical hypotheses on proteins ... -
A Revised View of the LSU Gene Family: New Functions in Plant Stress Responses and Phytohormone Signaling
(MDPI, 2023-02)LSUs (RESPONSE TO LOW SULFUR) are plant-specific proteins of unknown function that were initially identified during transcriptomic studies of the sulfur deficiency response in Arabidopsis. Recent functional studies have ... -
AciDB 1.0: a database of acidophilic organisms, their genomic information and associated metadata
(OXFORD UNIV PRESS, 2020-10-01)Motivation: There are about 600 available genome sequences of acidophilic organisms (grow at a pH<5) from the three domains of the Tree of Life. Information about acidophiles is scattered over many heterogeneous sites ... -
Anaerobic RSH-dependent tellurite reduction contributes to Escherichia coli tolerance against tellurite
(SOC BIOLGIA CHILE, 2022-03)Background Tellurium is a rare metalloid that exerts high toxicity on cells, especially on bacteria, partly due to reactive oxygen species (ROS) generation. Moreover, it has also been observed that tellurite can target ... -
ATP6V(0)d2 controls Leishmania parasitophorous vacuole biogenesis via cholesterol homeostasis
(PUBLIC LIBRARY SCIENCE, 2019)V-ATPases are part of the membrane components of pathogen-containing vacuoles, although their function in intracellular infection remains elusive. In addition to organelle acidification, V-ATPases are alternatively implicated ... -
Bacterially produced metabolites protect C. elegans neurons from degeneration
(Public Library of Science, 2020-03)Caenorhabditis elegans and its cognate bacterial diet comprise a reliable, widespread model to study diet and microbiota effects on host physiology. Nonetheless, how diet influences the rate at which neurons die remains ... -
Bioinformatic analyses of unique (orphan) core genes of the genus Acidithiobacillus: Functional inferences and use as molecular probes for genomic and metagenomic/transcriptomic interrogation
(Facultad de Ciencias, 2016)Using phylogenomic and gene compositional analyses, five highly conserved gene families have been detected in the core genome of the phylogenetically coherent genus Acidithiobacillus of the class Acidithiobacillia. These ... -
Cátedras del Futuro: C. elegans: ¿cómo un gusano nos puede ayudar a comprender mejor enfermedades como el Parkinson y el Alzheimer?
(Chile. Universidad Mayor, 2019-09-05)En una nueva fecha del ciclo de charlas “Cátedras del Futuro”, la Dra. Andrea Calixto, académica del Centro de Genómica y Bioinformática U. Mayor, que presentó los resultados de las investigaciones que durante 4 años ha ... -
Cátedras del Futuro: ¿Cambiemos el mundo? Un genoma a la vez
(Chile. Universidad Mayor, 2019-06-26)La segunda fecha de este ciclo de conferencias tuvo como protagonista al Dr. Patricio Manque, Vicerrector de Investigación, quien presenta la charla “¿Cambiemos el mundo? Un genoma a la vez”. La jornada, llevada a cabo el ... -
Chloropicophyceae, a new class of picophytoplanktonic prasinophytes
(Chile. Universidad Mayor, 2016)Prasinophytes are a paraphyletic group of nine lineages of green microalgae that are currently classified either at the class or order level or as clades without formal taxonomic description. Prasinophyte clade VII comprises ... -
Comparative genomics sheds light on transcription factor-mediated regulation in the extreme acidophilic Acidithiobacillia representatives
(Elsevier Masson s.r.l., 2024-01)Extreme acidophiles thrive in acidic environments, confront a multitude of challenges, and demonstrate remarkable adaptability in their metabolism to cope with the ever-changing environmental fluctuations, which encompass ... -
ConnecTF: A platform to integrate transcription factor-gene interactions and validate regulatory networks
(OXFORD UNIV PRESS INC, 2021-04-28)Deciphering gene regulatory networks (GRNs) is both a promise and challenge of systems biology. The promise lies in identifying key transcription factors (TFs) that enable an organism to react to changes in its environment. ... -
Deciphering the functional diversity of DNA-binding transcription factors in Bacteria and Archaea organisms
(Public Library of Science, 2020-08)DNA-binding Transcription Factors (TFs) play a central role in regulation of gene expression in prokaryotic organisms, and similarities at the sequence level have been reported. These proteins are predicted with different ... -
Deep Sequencing Reveals the Complete Genome and Evidence for Transcriptional Activity of the First Virus-Like Sequences Identified in Aristotelia chilensis (Maqui Berry)
(CIENCIAS, 2015)Here, we report the genome sequence and evidence for transcriptional activity of a virus-like element in the native Chilean berry tree Aristotelia chilensis. We propose to name the endogenous sequence as Aristotelia chilensis ... -
DEF8 and Autophagy-Associated Genes are Altered in Mild Cognitive Impairment, Probable Alzheimer’s Disease Patients and a Transgenic Model of the Disease
(IOS Press, 2021-02-19)Background:Disturbances in the autophagy/endolysosomal systems are proposed as early signatures of Alzheimer’s disease (AD). However, few studies are available concerning autophagy gene expression in AD patients. Objective:To ... -
Development of a Multiplex PCR Assay for Genotyping the Fish Pathogen Piscirickettsia salmonis Through Comparative Genomics
(FRONTIERS MEDIA SA, 2021-07-11)Piscirickettsia salmonis is a bacterial pathogen that severely impact the aquaculture in several countries as Canada, Scotland, Ireland, Norway, and Chile. It provokes Piscirickettsiosis outbreaks in the marine phase of ... -
Dormant but Active: Chilling Accumulation Modulates the Epigenome and Transcriptome ofPrunus aviumDuring Bud Dormancy
(Frontiers Media S.A., 2020-07)Temperate deciduous fruit tree species like sweet cherry (Prunus avium) require long periods of low temperatures to trigger dormancy release and flowering. In addition to sequence-based genetic diversity, epigenetic variation ...